Search results

• Head and neck carcinomas oncogenesis and prognostic factors

  Molecular studies of carcinomas of the upper respiratory tract, including oncogenetic pathways and translational studies related to prognosis and t...

  Research – Research lines

• Transcriptional expression profiles involved in molecular mechanisms of carcinogenesis

  We focus mainly on prostate, breast, urologic, skin, gastrointestinal and lung tumors.

  Research – Research lines

• Genetic and epigenetic diagnosis of autoinflammatory disease

  Directed by Dr. Juan Ignacio Arostegui Extending knowledge of genetic diagnostic tools to improve the determination and management of patients wit...

  Research – Research lines

• Molecular determination of the T-cell specific immune response

  Directed by Dr. Europa Azucena González Study of the T-cell specific immune response, based on molecular and especially genetic definition of the...

  Research – Research lines

• Cellular immunotherapy for the treatment of cancer and other immune-mediated diseases

  Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...

  Research – Research lines

• Molecular and epigenetic mechanisms responsible for the persistent deleterious effects in target tissue exposed to steroidal hormones

  Translational approach in humans and animal models.

  Research – Research lines

• Neural correlates of mood- and anxiety-related disorders

  Directed by Joaquim Raduà We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brai...

  Research – Research lines

• Development of neuroimaging-based diagnostic and treatment prediction tools

  Directed by Joaquim Raduà We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and o...

  Research – Research lines

• Evidence-based syntheses in mental health

  Directed by Joaquim Raduà We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in me...

  Research – Research lines

• Integrative genetic profile and identification diagnostic markers

  In order to achieve the complete global genetic landscape of these rare tumors we are studying the molecular profile of poorly characterized Non-Ho...

  Research – Research lines

• Study of intratumoral heterogeneity

  Data already obtained in the analysis of pediatric NHL shows the presence of intratumoral heterogeneity that may represent the existence of differe...

  Research – Research lines

• Identification of genetic biomarkers and drug targets

  Our final goal is to identify target genes/pathways that can be useful biomarkers in the management of pediatric NHL. In detail, we aim to identify...

  Research – Research lines

• 1. Ischemia-reperfusion injury and expanding criteria for liver graft acceptance

  Maintaining the viability of organs from their recovery to transplantation is a key factor for transplant success and graft survival. Organ damage...

  Research – Research lines

• 2. Endoscopic management of biliary complications following liver transplantation

  The study of biliary complications after liver transplantation has high clinical relevance, due it relatively high incidence, complexity of managem...

  Research – Research lines

• 3. Expanding indications for liver transplantation in relation to pre-existing portal vein thrombosis and portal hypertension

  It is widely known that portal vein thrombosis is a serious complication of chronic liver disease, and the prognosis of liver transplantation depen...

  Research – Research lines

• 4. Expanding indications for transplantation for malignant tumors – hilar cholangiocarcinoma and colorectal cancer liver metastases

  The decrease in the number of patients on liver transplant waiting lists due to the advent of effective treatment for hepatitis C virus has generat...

  Research – Research lines

• 5. Alloimmune response, complications associated with immunosupression, and operational tolerance

  Treatment with immunosupression is associated with a series of risks for the transplanted patient, making minimization key to optimizing post-trans...

  Research – Research lines

• 6. Prevention and treatment of cardiovascular risk factors following liver transplantation

  Cardiovascular diseases represent one of the most common causes of long-term morbidity and mortality after liver transplantation. This group focuse...

  Research – Research lines

• Clinical applicability of genomic copy-number alterations and aneuploidy

  Chromosomal aneuploidy results in the acquisition of copy-number alterations, which occur early in tumorigenesis and are positively selected throug...

  Research – Research lines

• Intratumor heterogeneity as a novel biomarker in colorectal cancer

  Elucidating the role of genomic instability, which represents the molecular engine that fuels intratumor heterogeneity in carcinomas, is critical f...

  Research – Research lines