Search results

• N-glycosilation channelopathies and synaptic function

  Investigation how the activity of synaptic proteins and the synaptic function is affected by physiological and pathological N-glycosylation and its...

  Research – Research lines

• Utility of ECG imaging in locating abnormal conduction zones and in mapping arrhythmias.

  This involves obtaining images of the heart’s electrical activity in a noninvasive manner in order to apply this knowledge to developing ablation s...

  Research – Research lines

• Role of stimulation of the conduction system in cardiac stimulation.

  Study of new physiologic stimulation techniques. Assessment of results and complications. 

  Research – Research lines

• Study of the utility of new mapping tools in ablation of ventricular tachycardia

  Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...

  Research – Research lines

• Biomarkers, transplant immunology and cell therapy in renal and pancreatic transplantation.

  Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...

  Research – Research lines

• New technologies and biomarkers in dialysis

  Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...

  Research – Research lines

• Pathophisiology and innovative therapies in acute and chronic kidney disease

  Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...

  Research – Research lines

• Artificial intelligence

  Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...

  Research – Research lines

• Immune response in hepatitis B and D

  Directed by Sabela Lens We investigate the mechanisms of the immune response in chronic HBV and HDV infection to identify determinants of viral co...

  Research – Research lines

• Autoimmune and cholestatic liver diseases

  Directed by Maria Carlota Londoño Research focuses on autoimmune and cholestatic liver diseases, including autoimmune hepatitis, primary biliary c...

  Research – Research lines

• Epidemiology of drug-induced liver injury and Wilson’s disease

  Directed by Xavier Forns We analyze the epidemiology and clinical impact of drug-induced liver injury (DILI), including medications, herbals, and...

  Research – Research lines

• CAR-T cells for the treatment of solid tumours

  After the success of CAR-T cells in hematologic malignancies, the translation of CAR-T cells to solid tumours is the next big challenge in the fiel...

  Research – Research lines

• CAR-T cells for the treatment of hematologic malignancies

  Resistance to CD19-CAR-T cells in hematologic malignancies can appear linked to loss or downregulation of CD19 expression or an immunosuppressive t...

  Research – Research lines

• Understanding the limitations of CAR-T cells in preclinical studies

  The progress of CAR-T cells is limited by a poor understanding of how the design and signaling of these CAR proteins affect T cell efficacy and per...

  Research – Research lines

• Other cancer immunotherapies and combination treatments

  While T-cell based immunotherapies have revolutionized cancer treatment, a majority of patients fail to respond or relapse after a certain period o...

  Research – Research lines

• Development, evaluation and implementation of digital technologies in the field of mental health

  New digital technologies have opened a wide range of opportunities and challenges in the mental health field. During the last decade, our team have...

  Research – Research lines

• Critical conditions for disease onset or prognosis

  To evaluate clinical and molecular features that may condition disease onset, severity, evolution and co-morbidities. Description of the natural hi...

  Research – Research lines

• Identification of genes responsible for genetic disorders

  The strategic objective of this research line is to investigate the genetic, anatomopathological and biochemical bases, as well as the physiopathol...

  Research – Research lines

• Physiopathology of disease

  To search for the physiopatological bases of these diseases we use a combination of the classical and advanced omics technologies (metabolomics, pr...

  Research – Research lines

• Validation of models, mechanisms, and biomarkers of disease

  To confirm the pathogenicity of a certain gene or molecular mechanism, we validate cell models derived from patient to study the disease. We use fi...

  Research – Research lines