Líneas de investigación

• Neural correlates of mood- and anxiety-related disorders

  We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brain differences associated with mental disorders, specially mood- and anxiety-related disorders.

• Development of neuroimaging-based diagnostic and treatment prediction tools

  We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and outcome prediction in mental disorders, specially mood- and anxiety-related disorders.

• Evidence-based syntheses in mental health

  We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in mental disorders, specially mood- and anxiety-related disorders. Although our focus is on neuroimaging, we are also interested in clinical risk and prognostic factors. We have developed and validated several tools to this end (e.g., Seed-based d Mapping), and we participate in the international ENIGMA consortium.

• Digital interventions for depression and anxiety

  We develop and evaluate internet-based cognitive behavioural therapy (iCBT) programs to expand access to evidence-based treatments. Its standardized format supports our goal of identifying which interventions work for whom, including the neurobiological predictors of treatment outcome. Current projects include clinical trials in obsessive–compulsive disorder and the development of a program tailored to university and research settings.