Sobre mí

Jefe de grupo del Grupo 'Predisposición genética en el cáncer gastrointestinal' del FRCB-IDIBAPS en Barcelona. Durante más de 30 años, ha trabajado en enfermedades monogénicas/heredarias humanas y, más recientemente, en enfermedades humanas complejas como el cáncer colorrectal, el cáncer gástrico y el cáncer de páncreas. Fue coordinador de las Acciones COST BM1206 y CA17118 (2013-2022) y reconocido como Jefe de Grupo en su institución (2015). Sus actividades de investigación han dado lugar a más de 200 artículos en revistas internacionales de gran impacto y ha atraído a un gran número de citas (actualmente 8.203), con un índice H de 48.

Publicaciones destacadas

  • BMPR2 as a novel predisposition gene for hereditary colorectal polyposis

    Autores: Bonjoch L; Fernandez-Rozadilla C; Alvarez-Barona M; Lopez-Novo A; Herrera-Pariente C; Amigo J; Bujanda L; Remedios D; Dacal A; Cubiella J; Balaguer F; Fernández-Bañares F; Carracedo A; Jover R; Castellvi-Bel S; Ruiz-Ponte C.
    Referencia: Gastroenterology 2023.
  • Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

    Autores: Fernandez-Rozadilla, C; Timofeeva, M; Chen, ZS; Law, P; Thomas, M; Bien, S; Diez-Obrero, V; Li, L; Fernandez-Tajes, J; Palles, C; Sherwood, K; Harris, S; Svinti, V; McDonnell, K; Farrington, S; Studd, J; Vaughan-Shaw, P; Shu, XO; Long, JR; Cai, QY; Guo, XY; Lu, YC; Scacheri, P; Studd, J; Huyghe, J; Harrison, T; Shibata, D; Haiman, C; Devall, M; Schumacher, F; Melas, M; Rennert, G; Obón-Santacana, M; Martín-Sánchez, V; Moratalla-Navarro, F; Oh, JH; Kim, J; Jee, SH; Jung, KJ; Kweon, SS; Shin, MH; Shin, A; Ahn, YO; Kim, DH; Oze, I; Wen, WQ; Matsuo, K; Matsuda, K; Tanikawa, C; Ren, ZF; Gao, YT; Jia, WH; Potter, J; Jenkins, M; Win, AK; Pai, R; Figueiredo, J; Haile, R; Gallinger, S; Woods, M; Newcomb, P; Shibata, D; Cheadle, J; Kaplan, R; Maughan, T; Kerr, R; Kerr, D; Kirac, I; Böhm, J; Mecklin, LP; Jousilahti, P; Knekt, P; Aaltonen, L; Rissanen, H; Pukkala, E; Eriksson, J; Cajuso, T; Hänninen, U; Kondelin, J; Palin, K; Tanskanen, T; Renkonen-Sinisalo, L; Zanke, B; Männistö, S; Albanes, D; Weinstein, S; Ruiz-Narvaez, E; Palmer, J; Buchanan, D; Platz, E; Visvanathan, K; Ulrich, C; Siegel, E; Brezina, S; Gsur, A; Campbell, P; Chang-Claude, J; Hoffmeister, M; Brenner, H; Slattery, M; Potter, J; Tsilidis, K; Schulze, M; Gunter, M; Murphy, N; Castells, A; Castellví-Bel, S; Moreira, L; Arndt, V; Shcherbina, A; Stern, M; Pardamean, B; Bishop, T; Giles, G; Southey, M; Idos, G; McDonnell, K; Abu-Ful, Z; Greenson, J; Shulman, K; Lejbkowicz, F; Offit, K; Su, YR; Steinfelder, R; Keku, T; van Guelpen, B; Hudson, T; Hampel, H; Pearlman, R; Berndt, S; Houlston, R; Martinez, ME; Thomas, S; Corley, D; Pharoah, P; Larsson, S; Yen, Y; Lenz, HJ; White, E; Li, L; Doheny, K; Pugh, E; Shelford, T; Chan, AD; Cruz-Correa, M; Lindblom, A; Shibata, D; Joshi, A; Schafmayer, C; Scacheri, P; Kundaje, A; Nickerson, D; Schoen, R; Hampe, J; Stadler, Z; Vodicka, P; Vodickova, L; Vymetalkova, V; Papadopoulos, N; Edlund, C; Gauderman, W; Thomas, D; Shibata, D; Toland, A; Markowitz, S; Kim, A; Gruber, S; van Duijnhoven, F; Feskens, E; Sakoda, L; Gago-Dominguez, M; Wolk, A; Naccarati, A; Pardini, B; FitzGerald, L; Lee, SC; Ogino, S; Bien, S; Kooperberg, C; Li, C; Lin, Y; Prentice, R; Qu, CH; Bézieau, S; Tangen, C; Mardis, E; Yamaji, T; Sawada, N; Iwasaki, M; Haiman, C; Le Marchand, L; Wu, A; Qu, CX; McNeil, C; Coetzee, G; Hayward, C; Deary, I; Harris, S; Theodoratou, E; Reid, S; Walker, M; Ooi, L; Moreno, V; Casey, G; Gruber, S; Tomlinson, I; Zheng, W; Dunlop, M; Houlston, R; Peters, U.
    Referencia: Nature Genetics 2023.
  • Germline mutations in WNK2 could be associated with serrated polyposis syndrome

    Autores: Soares de Lima Y, Arnau-Collell C, Muñoz J, Herrera-Pariente C, Moreira L, Ocaña T, Díaz-Gay M, Franch-Expósito S, Cuatrecasas M, Carballal S, Lopez-Novo A, Moreno L, Fernàndez G, Díaz de Bustamante A, Peters S, Sommer AK, Spier I, Te Paske IBAW, van Herwaarden YJ, Castells A, Bujanda L, Capellà G, Steinke-Lange V, Mahmood K, Joo JE, Arnold J, Parry S, Macrae FA, Winship IM, Rosty C, Cubiella J, Rodríguez-Alcalde D, Holinski-Feder E, de Voer R, Buchanan DD, Aretz S, Ruiz-Ponte C, Valle L, Balaguer F, Bonjoch L, Castellvi-Bel S .
    Referencia: Journal Of Medical Genetics 2023.
  • Evaluating the Potential of Polygenic Risk Score to Improve Colorectal Cancer Screening

    Autores: Arnau-Collell C; Díez-Villanueva A; Bellosillo B; Augé JM; Muñoz J; Guinó E; Moreira L; Serradesanferm A; Pozo A; Tora-Rocamora I; Bonjoch L; Ibañez-Sanz G; Obon-Santacana M; Moratalla-Navarro F; Sanz-Pamplona R; Márquez CM; Miret RR; Berbegal RP; Velasco GP; Rodríguez CH; Grau J; Castells A; Borras JM; Bessa X; Moreno V; Castellví-Bel S; CRIPREV consortium.
    Referencia: Cancer Epidemiology Biomarkers & Prevention 2022.
  • Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility

    Autores: Arnau-Collell, Coral; Soares de Lima, Yasmin; Diaz-Gay, Marcos; Munoz, Jenifer; Carballal, Sabela; Bonjoch, Laia; Moreira, Leticia; Lozano, Juan Jose; Ocana, Teresa; Cuatrecasas, Miriam; Diaz de Bustamante, Aranzazu; Castells, Antoni; Capella, Gabriel; Bujanda, Luis; Cubiella, Joaquin; Rodriguez-Alcalde, Daniel; Balaguer, Francesc; Ruiz-Ponte, Clara; Valle, Laura; Moreno, Victor; Castellvi-Bel, Sergi.
    Referencia: Journal Of Medical Genetics 2020.
  • Germline biallelic MCM8 variants are associated with early-onset Lynch-like syndrome

    Autores: Golubicki M, Bonjoch L, Acuña-Ochoa JG, Díaz-Gay M, Muñoz J, Cuatrecasas M, Ocaña T, Iseas S, Mendez G, Cisterna D, Schubert SA, Nielsen M, van Wezel T, Goldberg Y, Pikarsky E, Robbio J, Roca E, Castells A, Balaguer F, Antelo M, Castellví-Bel S .
    Referencia: Jci Insight 2020.
  • Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer

    Autores: Bonjoch, Laia; Franch-Exposito, Sebastia; Garre, Pilar; Belhadj, Sami; Munoz, Jenifer; Arnau-Collell, Coral; Diaz-Gay, Marcos; Gratacos-Mulleras, Anna; Raimondi, Giulia; Esteban-Jurado, Clara; Soares de Lima, Yasmin; Herrera-Pariente, Cristina; Cuatrecasas, Miriam; Ocana, Teresa; Castells, Antoni; Fillat, Cristina; Capella, Gabriel; Balaguer, Francesc; Caldes, Trinidad; Valle, Laura; Castellvi-Bel, Sergi.
    Referencia: Gastroenterology 2020.
  • Using linkage studies combined with whole-exome sequencing to identify novel candidate genes for familial colorectal cancer

    Autores: Toma, Claudio; Diaz-Gay, Marcos; Franch-Exposito, Sebastia; Arnau-Collell, Coral; Overs, Bronwyn; Munoz, Jenifer; Bonjoch, Laia; de Lima, Yasmin Soares; Ocana, Teresa; Cuatrecasas, Miriam; Castells, Antoni; Bujanda, Luis; Balaguer, Francesc; Cubiella, Joaquin; Caldes, Trinidad; Fullerton, Janice M; Castellvi-Bel, Sergi.
    Referencia: International Journal Of Cancer 2020.
  • Approaches to functionally validate candidate genetic variants involved in colorectal cancer predisposition.

    Autores: Bonjoch L, Mur P, Arnau-Collell C, Vargas-Parra G, Shamloo B, Franch-Expósito S, Pineda M, Capellà G, Erman B, Castellví-Bel S .
    Referencia: Molecular Aspects Of Medicine 2019.
  • Mutational Signatures in Cancer (MuSiCa): a web application to implement mutational signatures analysis in cancer samples

    Autores: Diaz-Gay, Marcos; Vila-Casadesus, Maria; Franch-Exposito, Sebastia; Hernandez-Illan, Eva; Jose Lozano, Juan; Castellvi-Bel, Sergi;.
    Referencia: Bmc Bioinformatics 2018.

Proyectos destacados

  • Twinning for a European consortium of rectal cancer research institutions through stepping up scientific, technological and innovation excellence of IORS (STEPUPIORS)

    Investigador/a principal: Sergi Castellvi Bel
    Financiador: European Commission
    Código: HE_WD_21
    Duración: 01/10/2022 - 30/09/2025
  • Colorectal cancer in adolescents and young adults: identification of germline predisposition and somatic insults by a comprehensive multiomic characterization

    Investigador/a principal: Sergi Castellvi Bel
    Financiador: Fundacion Cientifica de la Asociacion Espanola contra el Cancer
    Código: AECC_Proyectos21
    Duración: 01/12/2021 - 30/11/2024
  • Germline predisposition to serrated polyposis syndrome: functional charaterization of candidate genes by CRISPR-CAS and organoid modeling

    Investigador/a principal: Sergi Castellvi Bel
    Financiador: Fundació La Marató de TV3
    Código: TV3_Minoritaries_20
    Duración: 30/03/2021 - 29/03/2024
  • Germline predisposition to colorectal cancer: functional characterization of new genes by CRISPR/CAS and organoid modeling (PARAGON)

    Investigador/a principal: Sergi Castellvi Bel
    Financiador: Instituto de Salud Carlos III
    Código: PI20/00113
    Duración: 01/01/2021 - 31/12/2023
  • Identifying biomarkers through translational research for prevention and stratification of colorectal cancer (TRANSCOLONCAN)

    Investigador/a principal: Sergi Castellvi Bel
    Financiador: European Comission (EU)
    Código: H2020-CA17118
    Duración: 01/11/2018 - 30/09/2023