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Chromosomal aneuploidy results in the acquisition of copy-number alterations, which occur early in tumorigenesis and are positively selected throug...
Elucidating the role of genomic instability, which represents the molecular engine that fuels intratumor heterogeneity in carcinomas, is critical f...
There is growing evidence that whole-genome doubling occurs early in tumorigenesis and triggers genetically unstable near-tetraploid cells. In addi...
To understand the molecular mechanisms involved in the development and progression of liver disease and cancer, with a focus on the aberrant reprog...
To decipher mechanisms underpinning the detrimental impact of obesity in liver disease and cancer. This knowledge is crucial for advancements in tr...
To define the molecular and cellular mechanisms that regulate/dysregulate angiogenesis in liver disease and cancer and define their functional rele...
Directed by Lidia Sabater Our research focuses on how pathogenic autoantibodies drive neurodegenerative and demyelinating disorders, including ant...
Directed by Thaís Armangue This research focuses on autoimmune and inflammatory neurological diseases in children, identifying novel antigens in a...
Coordination of the transfer of basic research in advanced therapies from the Hospital Clínic to its clinical application, through the scientific e...
Research on the molecular and pathophysiological mechanisms of adverse drug reactions and implementation of active pharmacovigilance systems that a...
Optimization of methodological and statistical support for clinical research and full-service CRO for phase I-IV clinical trials sponsored by acade...
Search for quality and the extent and context of application of current ethical principles in clinical research projects. It is developed in group...
Development of studies to relate genetics with the activity and response to the action of drugs.
Active collaboration in national clinical research networks, such as SCReN (Spanish clinical Research Network), to carry out multicenter clinical r...
Directed by: Maria Angels Martínez Zamora To evaluate new insights in the knowledge of the origin and recurrence of endometriosis and adenomyosis...
Directed by: Marta del Pino To understand the natural history of HPV infection will allow us to improve both prevention strategies and related les...
Directed by Sabela Lens We develop integrated micro-elimination strategies for viral hepatitis (HBV/HDV/HCV) within the Hospital Clínic area and t...
Physiological characterization of AMPAR and interacting proteins (TARPs and CPT1C) in neurons and glial cells and the role in memory and sensibilit...
Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.
Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such...