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Thrombotic microangiopathies (TMAs) have matching symptoms but may be due to quite different causes. Differential diagnosis of thrombotic thrombocy...
Platelet-derived microparticles facilitate interaction with other cell groups and may have a prothrombotic effect in certain pathological situation...
We have built unique prospective cohorts for the clinical and biological characterization of at-risk and prodromal Parkinson’s disease cohorts, e.g...
We seek, set-up and introduce clinically meaningful biomarkers. Hence, we pioneered the alpha-synuclein seed amplification assay in CSF, being the...
We investigate the pathophysiological mechanisms and pathways to unravel novel therapeutic targets of neurodegenerative movement disorders using hu...
Our group is currently investigating the endogenous phenotype that determines the heterogeneity of pulmonary hypertension in chronic airway obstruc...
To characterize the cell proliferative process that underlies the development of pulmonary hypertension in patients with thromboembolic pulmonary d...
The group is currently involved in a randomized control trial evaluating the impact of a prehabilitation program in the setting of cardiac surgery....
We are working on several physiological proof-of-concept studies and have promoted three international, multicentre, randomized controlled trials.
We are currently undertaking research projects addressed to clinical risk assessment and service selection, promotion of healthy lifestyles, collab...
Mechanisms involved in sinonasal and bronchial development, inflammation, and remodeling.
Mechanisms involved in olfactory dysfunction (rhinitis, rhinosinusitis, septal perforation) and neurogenesis of sinonasal diseases, traumatic brain...
Genetic, immunological, and biochemical mechanisms of respiratory, food, and drug allergy.
Mechanisms and biomarkers involved in glucocorticoid resistance of respiratory and non-respiratory diseases.
Mechanisms of allergy and co-factors, regulation of cyclooxygenase, leukotriene, and prostaglandins (PGE2) and their receptors.
Anaphylactic reactions (mastocytosis, adapter molecules in the signaling of IgE). Antiinflammatory drug effect in eosinophils and epithelial cells...
Impact of skull base tumours in quality of life and olfaction. Different surgical approaches.
Neuronal and connectivity properties determining the emergent activity generated by neuronal networks. Aspects of spontaneous rhythmic neural activ...
How is the activity that underlies different brain states, how are the transitions across them and whether we can exogenously induce them.
We explore new forms to interface the brain, to maintain a dialogue with it by means of recording and stimulation. Currently we are exploring the u...