Cellular immunotherapy for the treatment of cancer and other immune-mediated diseases
Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...
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Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...
Translational approach in humans and animal models.
Directed by Joaquim Raduà We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brai...
Directed by Joaquim Raduà We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and o...
Directed by Joaquim Raduà We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in me...
In order to achieve the complete global genetic landscape of these rare tumors we are studying the molecular profile of poorly characterized Non-Ho...
Data already obtained in the analysis of pediatric NHL shows the presence of intratumoral heterogeneity that may represent the existence of differe...
Our final goal is to identify target genes/pathways that can be useful biomarkers in the management of pediatric NHL. In detail, we aim to identify...
Cell plasticity predisposes cells to malignant transformation. Tumor cells lose their previously normal identity and function and, through a cellul...
Normal cells and tissues are continuously adapting themselves to exogenous challenges. Stem cell plasticity is central to the adaptation and regene...
Inflammation has positive and negative functions. On the one hand, inflammation is a normal response of the body to infections and injury. The migr...
Maintaining the viability of organs from their recovery to transplantation is a key factor for transplant success and graft survival. Organ damage...
The study of biliary complications after liver transplantation has high clinical relevance, due it relatively high incidence, complexity of managem...
It is widely known that portal vein thrombosis is a serious complication of chronic liver disease, and the prognosis of liver transplantation depen...
The decrease in the number of patients on liver transplant waiting lists due to the advent of effective treatment for hepatitis C virus has generat...
Treatment with immunosupression is associated with a series of risks for the transplanted patient, making minimization key to optimizing post-trans...
Cardiovascular diseases represent one of the most common causes of long-term morbidity and mortality after liver transplantation. This group focuse...
Chromosomal aneuploidy results in the acquisition of copy-number alterations, which occur early in tumorigenesis and are positively selected throug...
Elucidating the role of genomic instability, which represents the molecular engine that fuels intratumor heterogeneity in carcinomas, is critical f...
There is growing evidence that whole-genome doubling occurs early in tumorigenesis and triggers genetically unstable near-tetraploid cells. In addi...