Causes and risk factors of Uveitis

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Uveitis is an uncommon disease that predominantly effects people aged 20 to 50 years; although it can occur at any age and even affects children.

The mechanisms that lead to Uveitis have not been fully elucidated even though a great deal of research is being carried out in this area to ascertain the cause.

In a variable percentage of cases, the doctor cannot find the cause of the uveitis and therefore diagnoses “idiopathic uveitis”.

Nevertheless, it is known that the following diseases can increase the risk of developing uveitis:

Cell with a membrane receptor

Immune-mediated diseases. Inflammatory bowel disease (Crohn’s disease, ulcerative colitis), juvenile idiopathic arthritis (JIA), spondyloarthropathies (ankylosing spondylitis, psoriatic arthritis, reactive arthritis), multiple sclerosis, etc.


Communicable diseases. Herpes, toxoplasmosis, tuberculosis, syphilis, HIV, Lyme disease, brucellosis, etc.

Eye receiving laser surgery

A history of severe eye trauma or previous eye surgery.

Cancer cell surrounded by healthy cells

Some types of cancer: lymphoma, leukaemia, melanoma, among others.

Substantiated information by:

Alfredo Adán Civera
Marina Mesquida Febrer
Víctor Llorens Bellés

Published: 20 February 2018
Updated: 3 December 2019

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