Two articles by IDIBAPS/ICREA involve ZEB1 in tumor invasiveness and muscle differentiation

ZEB proteins (ZEB1 and ZEB2) have recently gained great relevance in molecular oncology because their role promoting invasiveness and metastasis in a number of human cancers through the induction of stemness markers and repression of epithelial adhesion genes. Two articles published this month by the Group of Transcriptional Regulation of Gene Expression, an IDIBAPS team led by an ICREA professor, have found new roles for ZEB1 in tumor invasiveness and muscle differentiation