Research - Unit of Alzheimer's and Other Cognitive Disorders

The Alzheimer’s Disease and Other Cognitive Disorders Unit carries out different clinical and translational research projects that aim to improve diagnostic, monitoring and prognostic tools for the main neurodegenerative dementias, as well as research into their causes in order to advance knowledge that will allow for the development of effective therapies for these diseases. 

This research is carried out by the following group

The main lines of research are:

• Study of pre-clinical and early clinical stages in genetically determined dementias (genetic Alzheimer’s disease, genetic frontotemporal dementia, and genetic prion diseases). 
• Study of Alzheimer’s disease and other early-onset dementias. Epidemiology, clinical characterization, diagnostic and prognostic biomarkers, social aspects. 
• Healthy ageing continuum – Alzheimer’s disease, development and validation of cognitive, digital and biological screening tools, neuroimaging studies. 
• Characterization, diagnostic and prognostic markers in rare diseases that present with dementia: frontotemporal dementia, primary progressive aphasias, prion diseases. 
• Research into non-pharmacological interventions. 
• Pharmacological clinical trials.
• Sleep disturbances in neurodegenerative dementias.
• Neuropathology in neurodegenerative dementias and clinical-pathological studies. Collaboration with the Neurological Tissue Bank at the Hospital Clínic-IDIBAPS Biobank.

At present, there are several active projects in these lines of research and, every year, numerous articles are published in international scientific journals, as well as a large number of communications in national and international congresses.