Signs and symptoms of Acute Myeloid Leukaemia

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The signs and symptoms presented by AML patients are due to the inability of their bone marrow to correctly produce normal blood cells, which translates into:

Blood test tube with a low red blood cell count or anemia

Low red blood cell count (anaemia). This can cause a feeling of tiredness, weakness, dizziness, pallor, and so on.

Decreased platelets

Shortage of platelets (thrombocytopaenia). This can cause bleeding (in the skin: bruising, petechiae; in mucous membranes, nose, and so on)

Decreased immune system cells seen under the microscope

Shortage of white blood cells (leukopaenia/neutropaenia). This is expressed as fever and infections.

In some subtypes of leukaemia, particularly in acute promyelocytic leukaemia, there may be more severe bleeding as a result of blood clotting disorders.

Sometimes, the infiltration of blasts into other tissues causes:

Patient with swollen glands

Enlarged lymph nodes, liver or spleen.

Axillary lymph nodes

Scattered nodules or areas of thickened skin.

Inflamación de la boca

Inflammation of the gums.

Person holding hands to neck, sweating, pale, unable to breathe, feeling short of breath, short of breath, choking or breathlessness

Choking sensation.

Scale with a down arrow indicating a weight loss

Loss of weight or appetite.

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Substantiated information by:

Laia Guardia Roca
Marina Díaz Beyá

Published: 8 April 2019
Updated: 8 April 2019

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