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Metabolic syndrome, which is a set of risk factors that predispose to heart disease: diabetes, high cholesterol and excess sugar, for example.
These factors promote excess lipid synthesis and its transfer from adipose tissue (tissue where fat is stored) to the liver, making elimination difficult.
For this reason, the prevalence of the disease among patients with obesity or diabetes is 60-80%. The disease, however, also occurs in people without these risk factors and, in these cases, it is usually due to genetic causes. People affected by this genetic variant have a tendency to synthesise lipids or decrease their metabolism (processing); thus reducing their elimination and increasing accumulation.
The best way to prevent the disease is to follow a balanced diet and not be overweight or obese. Once the disease appears, weight loss and optimal control of metabolic risk factors (e.g. cholesterol, hypertension, diabetes) will promote its improvement and help prevent rapid progression.
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Substantiated information by:
Isabel Graupera Garcia-MilàHepatologist Senior SpecialistHepatology Service
Marta Cervera CarbonellNurseHepatology Service
Pere Ginès GibertHepatologistHepatology Service
Published: 19 August 2022
Updated: 26 August 2022
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