We use our own and third party cookies to offer you our services, customize and analyze your browsing and show you advertising related to your preferences. By continuing to browse, we consider that you accept its use. You can change the settings and get more information in the
Frontotemporal dementia, also known as Pick’s disease, is a group of neurodegenerative diseases that cause a progressive loss of neurons in the nervous system. In frontotemporal dementia, these neurons are mainly lost in the frontal and lateral parts of the brain, known as the frontal and temporal lobes.
Frontotemporal dementia is currently considered a rare disease, probably also because it may be under-diagnosed.
Sergi Borrego, Neurologist
The brain's frontal and temporal lobes are responsible for our social, executive and linguistic cognitive functions. This is why frontotemporal dementia is characterised by symptoms such as changes in personality and difficulties with language.
Frontotemporal dementias can be classified according to the symptoms of the disease, which may be behavioural problems and/or problems with language (aphasia). Therefore, we can distinguish between three clinical forms:
• Behavioural variant frontotemporal dementia: characterised by predominant atrophy in the brain's frontal lobes. It involves changes in the patient's personality, behaviour and emotions.
• Non-fluent/agrammatic variant of primary progressive aphasia: characterised by difficulties with speech and grammar.
• Semantic variant of primary progressive aphasia: characterised by predominant atrophy of the brain’s left temporal lobe. This leads to patients having problems with understanding words and recognising objects or people.
Furthermore, frontotemporal dementias are closely related to other syndromes that involve motor or movement problems. These include progressive supranuclear palsy, corticobasal syndrome and amyotrophic lateral sclerosis. It is common for patients with frontotemporal dementia to develop motor problems similar to these diseases as their condition progresses.
Sorry this content wasn't helpful to you. Send us your comment and we will take it into account to continue improving.
Thanks for your help!
An error has occurred and we were unable to send your opinion, please try again later.
The donations that can be done through this webpage are exclusively for the benefit of Hospital Clínic of Barcelona through Fundació Clínic per a la Recerca Biomèdica and not for BBVA Foundation, entity that collaborates with the project of PortalClínic.
Receive the latest updates related to this content.
Thank you for subscribing!
If this is the first time you subscribe you will receive a confirmation email, check your inbox
An error occurred and we were unable to send your data, please try again later.
Subscribe to the Newsletter of Clínic
Receive the latest news from our institution directly to your email.
Thanks for your subscription!
We have received your information. Check your inbox, in a few moments you will receive a confirmation email.
An error has occurred and we have not been able to send your data, please try again later.
More about assistance and health
Join our job pool
Hospital Clínic de Barcelona looks for talented professionals to cover job openings on a regular basis.