We use our own and third party cookies to offer you our services, customize and analyze your browsing and show you advertising related to your preferences. By continuing to browse, we consider that you accept its use. You can change the settings and get more information in the
Most of these diseases have an autosomal dominant inheritance pattern. This means you can get the disease by receiving the abnormal gene from only one of your parents. Men and women are at equal risk of inheriting the disease, and an affected person has a 50% chance of having a child with the disease (per pregnancy). However, even when the abnormal gene is inherited, the penetrance (probability of manifesting heart disease) and expressivity (degree of severity of the heart disease) can vary greatly, even within the same family.
There are also diseases with an autosomal recessive inheritance pattern, although these are much less frequent. In this case, men and women are at equal risk of inheritance, but for the disease to manifest itself the affected person must have received an altered gene from both parents. In this case, the risk of inheriting the disease will vary depending on whether the parents are affected, are only carriers of an altered gene, or are healthy individuals.
Finally, there are rare cases of sex-linked inheritance, where the abnormal gene affects the X chromosome. In these cases, incidence of the disease is higher in men, with women usually acting as carriers or presenting with less severe heart disease.
We are sorry, we are working to improve PortalCLÍNIC. Help us become better, tell us why
Thanks for your help!
An error has occurred and we were unable to send your opinion, please try again later.
The donations that can be done through this webpage are exclusively for the benefit of Hospital Clínic of Barcelona through Fundació Clínic per a la Recerca Biomèdica and not for BBVA Foundation, entity that collaborates with the project of PortalClínic.
Receive the latest updates related to this content.
Thank you for subscribing!
If this is the first time you subscribe you will receive a confirmation email, check your inbox
An error occurred and we were unable to send your data, please try again later.