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Chronic urticaria currently has no cure. All treatments are aimed at alleviating and controlling the symptoms. In a high percentage of cases, the symptoms abate spontaneously within five years, but in 11% the prevalence is more than five years.
H1 non-sedating antihistamines. They control and prevent the skin lesions. In those cases in which the response is not sufficient, the dose may be increased, always under medical supervision.
Biological treatments such as Omalizumab (anti-IgE monoclonal antibody) to alleviate symptoms that persist despite taking the maximum dose of antihistamines.
Immunosuppressants. Prescribed in those cases that respond to neither antihistamines nor biological treatments.