Causes and risk factors of Inflamatory Bowel Disease

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Although the exact cause of the disease is still unknown, we do know that different factors are involved in its development:


IBD is not a hereditary disease, but it does appear in people with a genetic predisposition, in whom interactions with different environmental factors (infections, tobacco, etc.) trigger an abnormal immune response which persists over time.

bacteria and germs

Various germs have been connected to the development of inflammatory bowel disease, but none have been confirmed as its cause. Antigens, substances that induce an immune response and which are found in the intestinal lumen (passageways), are believed to be the cause of inflammation of the bowels.

Substantiated information by:

Ingrid Ordas Jimenez
Marta Gallego Barrero

Published: 20 February 2018
Updated: 4 September 2020


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