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Showing 2741 - 2760 de 6607 results

  • Screening for liver fibrosis. A population-based study in European countries. The 'LiverScreen' project

    The aim of this project is to prove the cost-effectiveness of screening for liver fibrosis in general population using transient elastography.

    Research – Research lines
  • Studying different strategies to halt disease progression

    A multicenter, double-blind, placebo controlled randomized clinical trial to study the safety and efficacy of the combination of simvastatin plus r...

    Research – Research lines
  • Sleep and sleep disorders

    A clinical and electrophysiological assessment of normal sleep in humans and of sleep disorders including the anti-IgLON5 disease, REM sleep behavi...

    Research – Research lines
  • Epilepsy

    Characterization of the epileptogenic activity and the surgical and medical therapy of the refractory epilepsy using functional MRI, video-EEG and...

    Research – Research lines
  • Neuropathic pain

    Electrophysiological evaluation of the neuropathic pain using nocioceptive evoked potentials and other tools including the startle reaction.

    Research – Research lines
  • Motor control

    Assesment of the motor control in healthy subjects and in patients with neurological diseases using acoustic and somatosensorial stimul and prepulse.

    Research – Research lines
  • Precision screening, diagnosis, and staging for enhanced liver cancer outcomes

    Directed by Maria Reig  Effective stratification of patients according to their cancer risk is essential to ensure cost-effective screening progra...

    Research – Research lines
  • Non-invasive prognostic assessment by radiology in liver cancer

    Directed by Jordi Rimola   It is necessary to identify the radiological imaging biomarkers that have the potential to provide valuable prognostic...

    Research – Research lines
  • Predictive factors of treatment response in liver cancer

    Directed by Maria Reig  This research line focuses on identifying and understanding key predictive factors that influence the response to surgical...

    Research – Research lines
  • Identification of non-invasive biomarkers of liver injury and new signalling pathways of liver fibroproliferative processes

    Biochemical identification and clinical validation of non-invasive serological markers of liver disease and their complications. Identification of...

    Research – Research lines
  • Evaluation of new strategies to inhibit hepatocyte activity of FoxO1 or to modify the activity of specific Akt targets that have a therapeutic potential to stimulate functional liver regeneration in cirrhotic livers

    Experiments are being carried out in animal models of hepatic regeneration based on partial hepatectomy and toxicity induced by overdose with aceta...

    Research – Research lines
  • Establish new therapies for the normalisation of the intrahepatic vasculature in cirrhotic livers

    These new therapies focus on inhibiting the occurrence of mesenchymal endothelial transition phenomenon, increased endothelial connectivity, inhibi...

    Research – Research lines
  • Evaluation of the therapeutic potential of cerium oxide nanoparticles in experimental models of hepatocellular carcinoma and liver steatosis

    The effects of cerium oxide nanoparticles, antioxidant agents with liver tropism and superoxide dismutase and catalase activity are studied on anim...

    Research – Research lines
  • Evaluation of the utility of collagen matrix implants containing endothelial cells as a cell therapy to stimulate the regenerative layer of cirrhotic livers

    The potential therapeutic effects that healthy endothelial cells immersed in the matrices of collagen can have when interacting and communicating w...

    Research – Research lines
  • Modulation of macrophages to liver damage, regeneration and cancer through functionalised nanoparticles and gene therapy

    Nanoparticles are designed and synthesized to be incorporated by pro-inflammatory macrophages in the cirrhotic liver or by macrophages associated w...

    Research – Research lines
  • Basic and translational research

    Immuno-pathogenesis of HIV infection and mechanisms of HIV control Generation of new immunogens based on defective HIV-based vectors  Developme...

    Research – Research lines
  • Epidemiological research and public health

    Epidemiological studies based on cohorts (PISCIS, ART-CC, COHERE, EuroSida. PROBE-C) STDs in HIV-infected patients. Epidemiology, diagnosis, tre...

    Research – Research lines
  • Systemic vasculitis. Mechanisms involved in inflammation and vascular remodeling as a source of biomarkers of clinical utility and therapeutic innovation

    Accurate characterization of patient cohorts (systemic vasculitis) according to relevant outcomes (diease extent, relapsing disease, complication...

    Research – Research lines
  • Proliferation and apoptosis in pulmonary arterial hypertension: biomarkers and new therapies

    PH is a severe condition causing significant burden. Fortunately, recent advances in the understanding of the pathobiology of PH have prompted the...

    Research – Research lines
  • Interventions on lifestyle: exercise and other non-pharmacological actions to improve PH

    Targeting lifestyle in PH may improve the disease. To demonstrate it, an experimental model of PH, assessing the effects of exercise training on pl...

    Research – Research lines

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