Publicacions destacades

Single-cell RNA sequencing-derived signatures define response patterns to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma

Cappuyns, Sarah; Pique-Gili, Marta; Esteban-Fabro, Roger; Philips, Gino; Balaseviciute, Ugne;

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Van Cutsem, Eric; Lambrechts, Diether; Villanueva, Augusto; Dekervel, Jeroen; Llovet, Josep M.

Referència:
JOURNAL OF HEPATOLOGY 2025.
Transarterial chemoembolisation combined with lenvatinib plus pembrolizumab versus dual placebo for unresectable, non-metastatic hepatocellular carcinoma (LEAP-012) : a multicentre, randomised, double-blind, phase 3 study

Kudo, Masatoshi; Ren, Zhenggang; Guo, Yabing; Han, Guohong; Lin, Hailan;

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Dutcus, Corina; Dubrovsky, Leonid; Siegel, Abby B; Finn, Richard S; Llovet, Josep M.

Referència:
LANCET 2025.
Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma

Llovet, Josep M; Pinyol, Roser; Yarchoan, Mark; Singal, Amit G; Marron, Thomas U;

Schwartz, Myron; Pikarsky, Eli; Kudo, Masatoshi; Finn, Richard S.

Referència:
Nature Reviews Clinical Oncology 2024.
Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification

Montironi, Carla; Castet, Florian; Haber, Philipp K; Pinyol, Roser; Torres-Martin, Miguel;

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Villanueva, Augusto; Friedman, Scott L; Uzilov, Andrew; Sia, Daniela; Llovet, Josep M.

Referència:
GUT 2023.
Immunotherapies for hepatocellular carcinoma

Llovet, Josep M; Castet, Florian; Heikenwalder, Mathias; Maini, Mala K; Mazzaferro, Vincenzo;

Pinato, David J; Pikarsky, Eli; Zhu, Andrew X; Finn, Richard S.

Referència:
Nature Reviews Clinical Oncology 2022.
Molecular characterization of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis

Pinyol, Roser; Torrecilla, Sara; Wang, Huan; Montironi, Carla; Pique-Gili, Marta;

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Heikenwalder, Mathias; Sanyal, Arun; Friedman, Scott L; Sia, Daniela; Llovet, Josep M.

Referència:
JOURNAL OF HEPATOLOGY 2021.
NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Pfister, Dominik; Nunez, Nicolas Gonzalo; Pinyol, Roser; Govaere, Olivier; Pinter, Matthias;

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Amit, Ido; Knolle, Percy; Becher, Burkhard; Llovet, Josep M; Heikenwalder, Mathias.

Referència:
NATURE 2021.
Hepatocellular carcinoma

Llovet, Josep M; Kelley, Robin Kate; Villanueva, Augusto; Singal, Amit G; Pikarsky, Eli;

Roayaie, Sasan; Lencioni, Riccardo; Koike, Kazuhiko; Zucman-Rossi, Jessica; Finn, Richard S.

Referència:
Nature Reviews Disease Primers 2021.
Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

Hoshida, Yujin; Villanueva, Augusto; Kobayashi, Masahiro; Peix, Judit; Chiang, Derek Y;

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Bruix, Jordi; Friedman, Scott L; Kumada, Hiromitsu; Llovet, Josep M; Golub, Todd R.

Referència:
NEW ENGLAND JOURNAL OF MEDICINE 2008.
Sorafenib in advanced hepatocellular carcinoma

Llovet, Josep M; Ricci, Sergio; Mazzaferro, Vincenzo; Hilgard, Philip; Gane, Edward;

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Giannaris, Tom; Shan, Minghua; Moscovici, Marius; Voliotis, Dimitris; Bruix, Jordi.

Referència:
NEW ENGLAND JOURNAL OF MEDICINE 2008.