Pau Sancho-Bru
Publicacions destacades
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Autors: Argemie, Josepmaria; Latasa, Maria U.; Atkinson, Stephen R.; Blokhin, Ilya O.; Massey, Veronica; Gue, Joel P.; Cabezas, Joaquin; Lozano, Juan J.; Van Booven, Derek; Bell, Aaron; Cao, Sheng; Vernetti, Lawrence A.; Arab, Juan P.; Ventura-Cots, Meritxell; Edmunds, Lia R.; Fondevilla, Constantino; Starkel, Peter; Dubuquoy, Laurent; Louvet, Alexandre; Odena, Gemma; Gomez, Juan L.; Aragon, Tomas; Altamirano, Jose; Caballeria, Juan; Jurczak, Michael J.; Taylor, D. Lansing; Berasain, Carmen; Wahlestedt, Claes; Mongv, Satdarshan P.; Morgan, Marsha Y.; Sancho-Bru, Pau; Mathurin, Philippe; Furuya, Shinji; Lackner, Carolin; Rusyn, Ivan; Shah, Vijay H.; Thursz, Mark R.; Mann, Jelena; Avila, Matias A.; Bataller, Ramon;.Referència: Nature Communications 2019. -
Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis
Autors: Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P .Referència: Hepatology 2019. -
Expression of microRNA-155 in inflammatory cells modulates liver injury
Autors: Delia Blaya; Beatriz Aguilar-Bravo; Fengie Hao; Silvia Casacuberta-Serra; Mar Coll; Luis Perea; Julia Vallverdu; Isabel Graupera; Elisa Pose; Barquinero Mañez, Jordi; Francisco Javier Cubero; Juan Caballería; Pere Ginès; Pau Sancho-Bru.Referència: Hepatology 2018. -
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis
Autors: Coll M; Perea L; Boon R; Leite S; Vallverdú J; Mannaerts I; Smout A; El Taghdouini A; Blaya D; Rodrigo-Torres D; Graupera I; Aguilar-Bravo B; Chesne C; Najimi M; Sokal E; Lozano J; van Grunsven L; Verfaillie C; Sancho-Bru P.Referència: Cell Stem Cell 2018. -
Pentraxin-3 Modulates LPS-induced Inflammatory Response and Attenuates Liver Injury.
Autors: Perea L, Coll M, Sanjurjo L, Blaya D, Taghdouini AE, Rodrigo-Torres D, Altamirano J, Graupera I, Aguilar-Bravo B, Llopis M, Vallverdú J, Caballeria J, van Grunsven LA, Sarrias MR, Ginès P, Sancho-Bru P .Referència: Hepatology 2017. -
Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation
Autors: Blaya D, Coll M, Rodrigo-Torres D, Vila-Casadesús M, Altamirano J, Llopis M, Graupera I, Perea L, Aguilar-Bravo B, Díaz A, Banales JM, Clària J, Lozano JJ, Bataller R, Caballería J, Ginès P, Sancho-Bru P .Referència: Gut 2016. -
Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells
Autors: Coll M., Taghdouini A., Perea L., Mannaerts I., Vila-Casadesús M., Blaya D., Rodrigo-Torres D., Affò S., Morales-Ibanez O., Graupera I., Lozano J., Najimi M., Sokal E., Lambrecht J., Ginès P., Van Grunsven L., Sancho-Bru P..Referència: Scientific Reports 2015. -
The biliary epithelium gives rise to liver progenitor cells
Autors: Rodrigo-Torres, Daniel; Affo, Silvia; Coll, Mar; Morales-Ibanez, Oriol; Millan, Cristina; Blaya, Delia; Alvarez-Guaita, Anna; Rentero, Carles; Lozano, Juan Jose; Maestro, Miguel Angel; Solar, Myriam; Arroyo, Vicente; Caballeria, Joan; Van Grunsven, Leo A; Enrich, Carlos; Gines, Pere; Bataller, Ramon; Sancho-Bru, Pau.Referència: Hepatology 2014. -
CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis
Autors: Affo, Silvia; Morales-Ibanez, Oriol; Rodrigo-Torres, Daniel; Altamirano, Jose; Blaya, Delia; Dapito, Dianne H; Millan, Cristina; Coll, Mar; Caviglia, Jorge M; Arroyo, Vicente; Caballeria, Juan; Schwabe, Robert F; Gines, Pere; Bataller, Ramon; Sancho-Bru, Pau.Referència: Gut 2014. -
Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis
Autors: Sancho-Bru, Pau; Altamirano, Jose; Rodrigo-Torres, Daniel; Coll, Mar; Millan, Cristina; Jose Lozano, Juan; Miquel, Rosa; Arroyo, Vicente; Caballeria, Juan; Gines, Pere; Bataller, Ramon.Referència: Hepatology 2012.
Projectes destacats
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Desarrollo de una herramienta de cribado de nuevos fármacos para el tratamiento de la enfermedad hepática crónica a partir de un sistema in vitro hepático organotípico derivado de iPSC
Investigador/a principal: Pau Sancho BruFinançador: Instituto de Salud Carlos III (ISCIII)Codi: DTS18/00088Durada: 01/01/2019 - 31/12/2020 -
Liver-enriched Transcription Factors as Prognostic Markers and Therapeutic Targets in Alcoholic Hepatitis (LiverTF)
Investigador/a principal: Pau Sancho BruFinançador: National Institutes of Health (NIH)Codi: 5U01AA026972Durada: 22/09/2018 - 30/06/2020 -
Mecanismos implicados en la deficiente reparación tisular del hígado en enfermedades crónicas hepáticas. Nuevas dianas terapéuticas
Investigador/a principal: Pau Sancho BruFinançador: Instituto de Salud Carlos III (ISCIII)Codi: PI17/00673Durada: 01/01/2018 - 31/12/2020 -
Hepatic Microfluidic Bioreactor (HeMiBio)
Investigador/a principal: Pau Sancho BruFinançador: Institut D'investigacions Biomediques August Pi i Sunyer (Idibaps) (Sede); European Comission (EC) ; Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen)Codi: FP7-2010-Alt.Test (266777)Durada: 01/01/2011 - 31/12/2015 -
Understanding hepatoblastoma to design new personalized treatments (HB-Project)
Investigador/a principal: Pau Sancho BruCodi: AECC-Proyectos19Durada: 01/12/2019 - 30/11/2022