Sílvia Beà
Grup de recerca
- Patologia molecular en neoplàsies limfoides Accredited researcher (R3A)
Publicacions destacades
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Genomic and epigenomic insights into the origin, pathogenesis and clinical behavior of mantle cell lymphoma subtypes
Autors: Nadeu F, Martin-Garcia D, Clot G, Díaz-Navarro A, Duran-Ferrer M, Navarro A, Vilarrasa-Blasi R, Kulis M, Royo R, Gutiérrez-Abril J, Valdés-Mas R, López C, Chapaprieta V, Puiggros M, Castellano G, Costa D, Aymerich M, Jares P, Espinet B, Muntañola A, Ribera-Cortada I, Siebert R, Colomer D, Torrents D, Gine E, López-Guillermo A, Küppers R, Martin-Subero JI, Puente XS, Beà S, Campo E .Referència: Blood 2020. -
Cryptic insertions of the immunoglobulin light chain enhancer region near CCND1 in t(11;14)-negative mantle cell lymphoma
Autors: Fuster C, Martín-Garcia D, Balagué O, Navarro A, Nadeu F, Costa D, Prieto M, Salaverria I, Espinet B, Rivas-Delgado A, Terol MJ, Giné E, Forcada P, Ashton-Key M, Puente XS, Swerdlow SH, Beà S, Campo E .Referència: Haematologica 2020. -
CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma
Autors: Martín-Garcia D, Navarro A, Valdés-Mas R, Clot G, Gutiérrez-Abril J, Prieto M, Ribera-Cortada I, Woroniecka R, Rymkiewicz G, Bens S, de Leval L, Rosenwald A, Ferry JA, Hsi ED, Fu K, Delabie J, Weisenburger D, de Jong D, Climent F, O'Connor SJ, Swerdlow SH, Torrents D, Beltran S, Espinet B, González-Farré B, Veloza L, Costa D, Matutes E, Siebert R, Ott G, Quintanilla-Martinez L, Jaffe ES, López-Otín C, Salaverria I, Puente XS, Campo E, Beà S .Referència: Blood 2019. -
Improved classification of leukemic B-cell lymphoproliferative disorders using a transcriptional and genetic classifier.
Autors: Navarro A, Clot G, Martínez-Trillos A, Pinyol M, Jares P, González-Farré B, Martínez D, Trim N, Fernández V, Villamor N, Colomer D, Costa D, Salaverria I, Martín-Garcia D, Erber W, López C, Jayne S, Siebert R, Dyer MJS, Wiestner A, Wilson WH, Aymerich M, López-Guillermo A, Sánchez À, Campo E, Matutes E, Beà S .Referència: Haematologica 2017. -
Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia
Autors: Salaverria I., Martín-Garcia D., López C., Clot G., García-Aragonés M., Navarro A., Delgado J., Baumann T., Pinyol M., Martin-Guerrero I., Carrió A., Costa D., Queirós A., Jayne S., Aymerich M., Villamor N., Colomer D., González M., López-Guillermo A., Campo E., Dyer M., Siebert R., Armengol L., Beà S..Referència: Genes Chromosomes & Cancer 2015. -
CCND2 rearrangements are the most frequent genetic events in cyclin D1(-) mantle cell lymphoma
Autors: Salaverria, Itziar; Royo, Cristina; Carvajal-Cuenca, Alejandra; Clot, Guillem; Navarro, Alba; Valera, Alejandra; Song, Joo Y; Woroniecka, Renata; Rymkiewicz, Grzegorz; Klapper, Wolfram; Hartmann, Elena M; Sujobert, Pierre; Wlodarska, Iwona; Ferry, Judith A; Gaulard, Philippe; Ott, German; Rosenwald, Andreas; Lopez-Guillermo, Armando; Quintanilla-Martinez, Leticia; Harris, Nancy L; Jaffe, Elaine S; Siebert, Reiner; Campo, Elias; Bea, Silvia.Referència: Blood 2013. -
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma
Autors: Bea, Silvia; Navarro, Alba; Salaverria, Itziar; Martin-Garcia, David; Jares, Pedro; Gine, Eva; Nadeu, Ferran; Conde, Laura; Juan, Manel; Clot, Guillem; Lopez-Guerra, Monica; Moros, Alexandra; Roue, Gael; Aymerich, Marta; Villamor, Neus; Martinez, Antonio; Valera, Alexandra; Amador, Virginia; Hernandez, Luis; Rozman, Maria; Colomer, Dolors; Lopez-Guillermo, Armando; Campo, Elias.Referència: Proceedings Of The National Academy Of Sciences Of The United States Of America 2013. -
Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features
Autors: Navarro, Alba; Clot, Guillem; Royo, Cristina; Jares, Pedro; Hadzidimitriou, Anastasia; Agathangelidis, Andreas; Bikos, Vasilis; Darzentas, Nikos; Papadaki, Theodora; Salaverria, Itziar; Pinyol, Magda; Puig, Xavier; Palomero, Jara; Carmela Vegliante, Maria; Amador, Virgina; Martinez-Trillos, Alejandra; Stefancikova, Lenka; Wiestner, Adrian; Wilson, Wyndham; Pott, Christiane; Jose Calasanz, Maria; Trim, Nicola; Erber, Wendy; Sander, Birgitta; Ott, German; Rosenwald, Andreas; Colomer, Dolors; Gine, Eva; Siebert, Reiner; Lopez-Guillermo, Armando; Stamatopoulos, Kostas; Bea, Silvia; Campo, Elias.Referència: Cancer Research 2012. -
Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling
Autors: Hartmann, Elena M; Campo, Elias; Wright, George; Lenz, Georg; Salaverria, Itziar; Jares, Pedro; Xiao, Wenming; Braziel, Rita M; Rimsza, Lisa M; Chan, Wing-Chung; Weisenburger, Dennis D; Delabie, Jan; Jaffe, Elaine S; Gascoyne, Randy D; Dave, Sandeep S; Mueller-Hermelink, Hans-Konrad; Staudt, Louis M; Ott, German; Bea, Silvia; Rosenwald, Andreas.Referència: Blood 2010.
Projectes destacats
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Mutational landscape of follicular lymphoma at late relapse, early failure and histological transformation
Investigador/a principal: Sílvia Beà BobetFinançador: Fundació Privada Clínic per a la Recerca Biomèdica (Sede o evento); Asociación Española Contra el Cáncer (AECC) (Programa financiador competitivo); CIBERONC (Programa financiador competitivo)Codi: PROTE18020BEADurada: 01/11/2018 - 31/10/2022 -
Caracterización de la inestabilidad genómica y las mutaciones somáticas en linfoma de células del manto y su impacto pronostico
Investigador/a principal: Sílvia Beà BobetFinançador: Instituto de Salud Carlos III (FIS-ISCIII) (Programa financiador competitivo); IDIBAPS (Sede o evento)Codi: PI17/01061Durada: 01/01/2018 - 31/12/2011 -
Resistance mechanisms of molecular targeted therapies in mantle cell lymphoma (RESTMCL)
Investigador/a principal: Sílvia Beà BobetCodi: 201904-30Durada: 30/07/2020 - 29/07/2023 -
Comprehensive whole genome and exome sequence analysis in mantle cell lymphoma primary tumors
Investigador/a principal: Silvia BeàCodi: 20130410Durada: 01/01/2014 - 31/12/2016 -
Comprehensive whole genome and exome sequence analysis in mantle cell lymphoma primary tumours
Investigador/a principal: Silvia Beà BobetCodi: 12-0142Durada: 01/01/2012 - 31/12/2014