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Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered to be the most severe form of human viral hepatitis. Chro...
Physiological characterization of AMPAR and interacting proteins (TARPs and CPT1C) in neurons and glial cells and the role in memory and sensibilit...
Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.
Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such...
Study of the ionic channels that regulate the electrical activity of sensory neurons and how they are altered during the pathology. Identification...
To understand how neuron-glia communication contributes to synapse and neuronal loss, and modulates neuronal activity in neurodegeneration. A majo...
Investigation how the activity of synaptic proteins and the synaptic function is affected by physiological and pathological N-glycosylation and its...
This involves obtaining images of the heart’s electrical activity in a noninvasive manner in order to apply this knowledge to developing ablation s...
Study of new physiologic stimulation techniques. Assessment of results and complications.
Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...
Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...
Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...
Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...
Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...
There is no curative treatment for HBV infection. This is mainly due to the persistence of cccDNA (covalently closed circular DNA) in the nucleus o...
There are very few data on the role of the immune response (and especially of the specific or adaptive) in the viral events that characterize the n...
Despite the existence of an efficient hepatitis B vaccine for more than 30 years, hepatitis B virus (HBV) infection is still a global health proble...
Although most studies have focused on the analysis of T cell responses in chronic hepatitis B, humoral / B cell responses are important for prevent...
Significant scale-up of treatment among people who inject drugs (PWID) is crucial to achieve WHO hepatitis C virus (HCV) elimination targets. We ha...
Portal hypertension (PH) is the key driver of hepatic decompensation in patients with advanced chronic liver disease. Accordingly, interventions th...