Resultados de búsqueda

• Coordination of multinational projects and research networks

  Active collaboration in national clinical research networks, such as SCReN (Spanish clinical Research Network), to carry out multicenter clinical r...

  Investigación – Líneas de investigación

• Etiopathogenesis in endometriosis and adenomyosis

  Directed by: Maria Angels Martínez Zamora To evaluate new insights in the knowledge of the origin and recurrence of endometriosis and adenomyosis...

  Investigación – Líneas de investigación

• Human papillomavirus (HPV) infection and prevention

  Directed by: Marta del Pino To understand the natural history of HPV infection will allow us to improve both prevention strategies and related les...

  Investigación – Líneas de investigación

• Interplay between HBV, HDV and host factors: impact on liver disease progression

  Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered to be the most severe form of human viral hepatitis. Chro...

  Investigación – Líneas de investigación

• Glutamatergic signalling: functional interaction between AMPARs, auxiliary subunits and novel interacting proteins

  Physiological characterization of AMPAR and interacting proteins (TARPs and CPT1C) in neurons and glial cells and the role in memory and sensibilit...

  Investigación – Líneas de investigación

• Pathophysiology of the NMDAR receptor and personalised medicine for GRIN-related disorders.

  Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.

  Investigación – Líneas de investigación

• Ocular physiology: dry eye physiopathology and sensory neurons on the ocular surface. Pathophysiology of the drainage of aqueous humour and the physiopathology of glaucoma

  Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such...

  Investigación – Líneas de investigación

• Physiology and pathophysiology of pain and chronic itch. Study of the ion channels involved in neuronal excitability in the sensory nervous system

  Study of the ionic channels that regulate the electrical activity of sensory neurons and how they are altered during the pathology. Identification...

  Investigación – Líneas de investigación

• Microglia-neuron crosstalk in health and disease

  To understand how neuron-glia communication contributes to synapse and neuronal loss, and modulates neuronal activity in neurodegeneration. A majo...

  Investigación – Líneas de investigación

• N-glycosilation channelopathies and synaptic function

  Investigation how the activity of synaptic proteins and the synaptic function is affected by physiological and pathological N-glycosylation and its...

  Investigación – Líneas de investigación

• Utility of ECG imaging in locating abnormal conduction zones and in mapping arrhythmias.

  This involves obtaining images of the heart’s electrical activity in a noninvasive manner in order to apply this knowledge to developing ablation s...

  Investigación – Líneas de investigación

• Role of stimulation of the conduction system in cardiac stimulation.

  Study of new physiologic stimulation techniques. Assessment of results and complications. 

  Investigación – Líneas de investigación

• Study of the utility of new mapping tools in ablation of ventricular tachycardia

  Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...

  Investigación – Líneas de investigación

• Biomarkers, transplant immunology and cell therapy in renal and pancreatic transplantation.

  Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...

  Investigación – Líneas de investigación

• New technologies and biomarkers in dialysis

  Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...

  Investigación – Líneas de investigación

• Pathophisiology and innovative therapies in acute and chronic kidney disease

  Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...

  Investigación – Líneas de investigación

• Artificial intelligence

  Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...

  Investigación – Líneas de investigación

• Novel biomarkers and clinical relevance of the persistence of cccDNA in chronic HBV infection

  There is no curative treatment for HBV infection. This is mainly due to the persistence of cccDNA (covalently closed circular DNA) in the nucleus o...

  Investigación – Líneas de investigación

• Natural history of chronic HBV infection in different clinical situations

  There are very few data on the role of the immune response (and especially of the specific or adaptive) in the viral events that characterize the n...

  Investigación – Líneas de investigación

• Clinical, virological and immunological predictors of response after antiviral treatment interruption in chronic hepatitis B

  Despite the existence of an efficient hepatitis B vaccine for more than 30 years, hepatitis B virus (HBV) infection is still a global health proble...

  Investigación – Líneas de investigación