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Led by C. Mauvezin. Genomic instability is a hallmark of tumor cells, resulting from errors in mitotic progression such as prolonged mitosis, DNA...
Our scientific contributions to advancing knowledge in liver cancer during the last 15 years are summarized as follows: we contributed to the class...
The group contributed to the molecular classification of HCC (Hoshida, NEJM 2008, Chiang Cancer Research 2008) and to the generation of gene signat...
We developed an 11-gene signature able to predict response to immune checkpoint inhibitors in HCC (Haber Gastroenterology 2022). We also contribute...
We have molecularly characterized human NASH-HCC at the genomic and molecular levels (Pinyol Journal of Hepatology 2021).
Several studies led to the identification of Akt/mTOR pathway [Villanueva Gastroenterology, 2008), EGFR pathway (Keng, Nature Biotech 2009), IGF pa...
Gene-set (three genes) based diagnosis of HCC reported in Llovet, Gastroenterology 2006, and included in EASL-EORTC guidelines. In addition, we pro...
We have contributed to the molecular classification of iCCA (Sia, Gastroenterology 2013) and eCCA (Montal, Journal of Hepatology 2020). We identi...
The international RCT showing survival benefits for sorafenib vs placebo, presented at plenary session in ASCO (Llovet, New Engl J Med 2008) was a...
Examples: 1) Influence of introducing the construct of "cannabis risk use" with a co-created formative intervention on cannabis health literacy in...
Examples: 1) Workforce in Addictions - Valorisation in Europe (WAVE) 2) https://interglam.eu/ 3) https://www.deep-seas.eu/ 4) https://far-seas....
Example: IBM-ABJ: Motivational Brief Intervention combined with Game-Based Learning to improve retention in treatment of patients with alcohol-rela...
Directed by Silvia Beà To comprehensively characterize the genetic and molecular profiles of aggressive B-cell lymphomas in order to identify accu...
Directed by Dr. Isabel Vilaseca, Dr. F. Xavier Avilés and Dr. Neus Basté Multiomic characterisation of head and neck cancer and its impact in a...
We are interested in deciphering and dissecting the plasticity and heterogeneity of cancer-associated fibroblasrs (CAF) during cholangiocarcinogene...
Combining in vitro and in vivo systems with high throughput transcriptomics and bioinformatics, we aim to elucidate the functional role of cancer s...
Tumors are highly heterogeneous entities, and we are interested in investigating the interactions between heterogeneous cancer cells and the tumor...
Directed by Dr. Laura Mezquita Circulating and tissue biomarkers for immunotherapy in lung cancer Molecular characterization of lung cancer and...
Directed by Francesc Balaguer Dr. Balaguer's research focuses on the clinical and endoscopic characterization of hereditary and familial forms of...
Directed by Antoni Castells Dr. Castells’ research focuses on the evaluation of population-based strategies, assessment of risk factors to advance...