Resultados de búsqueda

• Early lung cancer (LC) diagnosis

  Directed by Dr. Angela Guirao  LC is highly prevalent and deadly. Yet, it can be cured if diagnosed early. To improve early LC diagnosis we are cu...

  Investigación – Líneas de investigación

• Biomechanical characterization of lung ECM in lung disease and ageing

  Advanced biophysical techniques, such as atomic force microscopy (AFM), enable precise measurement of lung tissue stiffness and elasticity at the n...

  Investigación – Líneas de investigación

• Advanced neuroimaging and AI for modeling neurodegenerative diseases

  Directed by Roser Sala-Llonch We focus on the development of cutting-edge methodologies, including algorithms for multimodal neuroimaging data and...

  Investigación – Líneas de investigación

• Neuropsychology and neuroimaging in neurodegenerative diseases

  Directed by Bàrbara Segura We aim to identify the mechanisms responsible for cognitive deficits in neurologic diseases using multimodal neuroimagi...

  Investigación – Líneas de investigación

• Digital interventions for depression and anxiety

  Co-directed by Joaquim Raduà and Miquel A. Fullana We develop and evaluate internet-based cognitive behavioural therapy (iCBT) programs to expand...

  Investigación – Líneas de investigación

• Artificial intelligence immunodiagnostics

  We develop artificial intelligence immunodiagnostics to predict patient outcomes from immune cell states in blood. By combining single-cell transcr...

  Investigación – Líneas de investigación

• Understanding human systemic cancer immunosurveillance and escape

  We aim to understand how human immunosurveillance shapes the earliest progenitors of cancer (Burdziak et al Science 2023). Most knowledge comes fro...

  Investigación – Líneas de investigación

• Multimodal artificial intelligence for clinically actionable insights

  We use multimodal artificial intelligence to understand how the immune system links diverse clinical conditions. By integrating radiology, patholog...

  Investigación – Líneas de investigación

• Early-phase and investigator-initiated clinical trials

  We design and conduct early-phase clinical trials and investigator-initiated studies to evaluate novel targeted agents and immunotherapies. Close c...

  Investigación – Líneas de investigación

• Molecular profiling and biomarker discovery in upper gastrointestinal cancers

  We perform comprehensive molecular and transcriptomic profiling of gastric, pancreatic, and biliary tract tumors to identify oncogenic drivers and...

  Investigación – Líneas de investigación

• Liquid biopsy for real-time tumor monitoring

  We develop and validate liquid biopsy technologies that detect tumor-derived nucleic acids in plasma, enabling non-invasive monitoring of tumor dyn...

  Investigación – Líneas de investigación

• Patient-derived and genetically engineered models

  We create patient-derived organoids, xenografts (PDXs), and genetically engineered mouse models that replicate the heterogeneity of upper GI tumors...

  Investigación – Líneas de investigación

• Upper GI cancer cell and stromal interactions

  We investigate how interactions among tumor cells, the immune system, and stromal components affect tumor progression and therapy resistance. Under...

  Investigación – Líneas de investigación

• Unravelling the role of lipid droplets in epithelial regeneration and infections

  Directed by Albert Herms  Lipid droplets are very well characterized in liver, muscle or adipose tissue, but little is known about their role in e...

  Investigación – Líneas de investigación

• Understanding mutant selection and early tumorigenesis in ageing epithelia

  Directed by Albert Herms  Epithelial tissues accumulate mutations as we age. We are applying mouse and human epithelioids, advanced primary self-m...

  Investigación – Líneas de investigación

• Neural correlates of aversive and appetitive learning

  Directed by Miquel A. Fullana We study the neurobiology of aversive and appetitive learning, primarily using fMRI. These processes have strong tra...

  Investigación – Líneas de investigación

• Asymptomatic monoclonal gammopathies, extramedullary involvement in multiple myeloma, real-world outcomes and clinical trials

  Directed by Laura Rosiñol Dachs Clinical and biological characterization of asymptomatic gammopathies and their progression, study of extramedulla...

  Investigación – Líneas de investigación

• CAR-T cells against BCMA in multiple myeloma: prognostic factors and development of new chimeric receptors

  Directed by Carlos Fernández de Larrea CAR-T therapy uses autologous T cells genetically modified. Despite efficacy, relapses occur and questions...

  Investigación – Líneas de investigación

• Cardiac involvement and targeted treatments in amyloidosis

  Directed by Carlos Fernández de Larrea Cardiac involvement is the main prognostic marker in AL amyloidosis. We assess the impact of combined strat...

  Investigación – Líneas de investigación

• Advancing therapeutic targets & clinical trials

  Through the previous research line of our experimental lab, our outpatients’ clinic, and our clinical trials team, we participate in the most innov...

  Investigación – Líneas de investigación