Resultados de búsqueda

• Autosomal dominant forms of neurodegenerative dementias and rare dementias

  Directed by Raquel Sánchez-Valle Sánchez‑Valle’s research focuses on characterizing the earliest stages of autosomal dominant dementia, including...

  Investigación – Líneas de investigación

• Sporadic Alzheimer’s disease

  Directed by Albert Lladó Lladó’s research explores the epidemiology, biomarkers, therapies, and social factors in sporadic Alzheimer’s disease. Th...

  Investigación – Líneas de investigación

• Dementia with lewy bodies and concomitant pathologies in Alzheimer’s disease

  Directed by Mircea Balasa Balasa’s research focuses on validating fluid and imaging biomarkers for earlier and more accurate diagnosis of Dementia...

  Investigación – Líneas de investigación

• The role of microglia and neuroinflammation in neurodegeneration

  Directed by Anna Martinez-Muriana Martinez-Muriana investigates how microglia and neuroinflammation drive neurodegeneration, with a particular foc...

  Investigación – Líneas de investigación

• Development and validation of cognitive assessment tools across the healthy aging–Alzheimer’s disease continuum

  Directed by Lorena Rami Rami’s research aims to define the neuropsychological features of the main neurodegenerative dementias. Her team develops...

  Investigación – Líneas de investigación

• Redox stress in aortic aneurysm formation and progression in Marfan syndrome

  Our aim is to find out which moieties and signaling pathways are impaired in redox physiology and stress in aortic vascular cells. We are also assa...

  Investigación – Líneas de investigación

• New pharmacological approaches to interfere in the Marfan syndrome-associated TGF-β hypersignaling

  We use TGF-β receptor peptide sequences to sequester soluble active TGF-β in excess to prevent the aortic aneurysm.

  Investigación – Líneas de investigación

• Non invasive characterization of arrhythmia substrate

  We aim to characterize the myocardial and electrical substrate in patients with atrial fibrillation and ventricular tachycardia in order to improve...

  Investigación – Líneas de investigación

• Characterization of cardiac mechanics in heart failure

  We aim to quantify and precisely describe underlying abnormalities in cardiac mechanics that could be corrected to improve the outcomes of patients...

  Investigación – Líneas de investigación

• Prediction of atrial fibrillation in patients at risk (Predict AF study)

  We aim to establish non invasive risk biomarkers based on imaging and blood tests to identify subjects that will develop atrial fibrillation in ord...

  Investigación – Líneas de investigación

• Identification of patients at risk of sudden death and heart failure after myocardial infarction

  We aim to characterize myocardial scar and cardiac remodelling to improve our identification of patients who will develop malignat ventricular arrh...

  Investigación – Líneas de investigación

• Identification of athletes at risk of sudden death

  We aim to characterize cardiac remodelling in response to exercise training and to identify those atletes at risk of presenting sudden death. Also,...

  Investigación – Líneas de investigación

• Characterization of hypertrophic hearts (INDEPTH-HCM)

  We aim to perform a in-depth myocardial characterization of hypertrophic cardiomyopathy: comprehensive multimodality imaging, tissue characterizati...

  Investigación – Líneas de investigación

• Identification of candidates for and impact of percutaneous therapies for heart valve disease

  We aim to understand the changes in valvular geometry and cardiac performance before and after implantation of novel percutanoeusly implanted devic...

  Investigación – Líneas de investigación

• Usefulness of non-invasive cardíac imaging in the identification of acute coronary syndromes

  We explore the additive diagnostic value of several non-invasive cardiac imaging modalities for the identification of acute coronary syndrome among...

  Investigación – Líneas de investigación

• To investigate the role of mitochondrial DNA in synapse elimination and neurodegeneration in genetic models of neurodegenerative diseases

  The loss of neuronal synapses is a phenomenon that occurs in the early stages of neurodegenerative disorders. We hypothesize that synaptic neurodeg...

  Investigación – Líneas de investigación

• To study the mechanisms that alter amyloid beta (Aβ) clearance and disposal of dysfunctional mitochondria

  Ab accumulation is a primary step of Alzheimer’s disease (AD). Noteworthy, while in early-onset familial AD increased Ab burden mainly results from...

  Investigación – Líneas de investigación

• Study the role of mitochondrial function in neuroinflammation and amyloid beta (Aβ)-induced cell death

  Neuroinflammation is a key pathological feature of Alzheimer’s disease (AD) that results primarily from the presence of chronically activated micro...

  Investigación – Líneas de investigación

• Psychotic and affective disorders in children and adolescents

  Directed by Immaculada Baeza  The research line has been active for the last fourteen years. Both diseases are considered neurobiological disorder...

  Investigación – Líneas de investigación

• Anorexia and other eating disorders

  Directed by Immaculada Baeza  Our group has studied clinical, neuropsychological and brain alterations in adolescents diagnosed with these disorde...

  Investigación – Líneas de investigación