José Alcamí

Grup de recerca

Sida i infecció per VIH Accredited researcher (R3A)

alcami@clinic.cat 0000-0003-0023-7377

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El compte de twitter de José .Aquest enllaç s'obre en una nova pestanya.

Publicacions destacades

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial

Autors:
Borobia, Alberto M; Carcas, Antonio J; Perez-Olmeda, Mayte; Castano, Luis; Jesus Bertran, Maria;

(...)

Ramon Arribas, Jose; Ochando, Jordi; Alcami, Jose; Belda-Iniesta, Cristobal; Frias, Jesus.

Referència: LANCET 2021.
Recommendations for measuring HIV reservoir size in cure-directed clinical trials

Autors:
Abdel-Mohsen, Mohamed; Richman, Douglas; Siliciano, Robert F; Nussenzweig, Michel C; Howell, Bonnie J;

(...)

Fox, Lawrence; Frank, Ian; Riley, James L; Tebas, Pablo; Montaner, Luis J.

Referència: NATURE MEDICINE 2020.
Association of a single nucleotide polymorphism in the ubxn6 gene with long-term non-progression phenotype in HIV-positive individuals

Autors:
Diez-Fuertes, F; De La Torre-Tarazona, H E; Calonge, E; Pernas, M; Bermejo, M;

(...)

Lopez-Galindez, C; Lathrop, M; Dopazo, J; Sakuntabhai, A; Alcami, J.

Referència: CLINICAL MICROBIOLOGY AND INFECTION 2020.
The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection

Autors:
Rodriguez-Mora, Sara; De Witid, Flore; Garcia-Perez, Javier; Bermejo, Mercedes; Lopez-Huertas, Maria Rosa;

(...)

Christ, Frauke; Debyser, Zeger; Vilchez, Juan Jesus; Coiras, Mayte; Alcami, Jose.

Referència: PLoS Pathogens 2019.
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

Autors:
Sliepen, Kwinten; Han, Byung Woo; Bontjer, Ilja; Mooij, Petra; Garces, Fernando;

(...)

Moore, John P; Shattock, Robin J; Bogers, Willy M; Wilson, Ian A; Sanders, Rogier W.

Referència: Nature Communications 2019.
IL-7 Induces SAMHD1 Phosphorylation in CD4+T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle

Autors:
Coiras, Mayte; Bermejo, Mercedes; Descours, Benjamin; Mateos, Elena; Garcia-Perez, Javier;

Lopez-Huertas, Maria-Rosa; Lederman, Michael M; Benkirane, Monsef; Alcami, Jose.

Referència: Cell Reports 2016.
Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon

Autors:
Lopez-Huertas, M R; Callejas, S; Abia, D; Mateos, E; Dopazo, A;

Alcami, J; Coiras, M.

Referència: NUCLEIC ACIDS RESEARCH 2010.
SDF-1/CXCL12 Production by Mature Dendritic Cells Inhibits the Propagation of X4-Tropic HIV-1 Isolates at the Dendritic Cell-T-Cell Infectious Synapse

Autors:
Gonzalez, Nuria; Bermejo, Mercedes; Calonge, Esther; Jolly, Clare; Arenzana-Seisdedos, Fernando;

Pablos, Jose L; Sattentau, Quentin J; Alcami, Jose.

Referència: JOURNAL OF VIROLOGY 2010.
Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

Autors:
Coiras, Mayte; Rosa Lopez-Huertas, Maria; Perez-Olmeda, Mayte; Alcami, Jose;

Referència: NATURE REVIEWS MICROBIOLOGY 2009.
ABSOLUTE DEPENDENCE ON KAPPA-B RESPONSIVE ELEMENTS FOR INITIATION AND TAT-MEDIATED AMPLIFICATION OF HIV TRANSCRIPTION IN BLOOD CD4 T-LYMPHOCYTES

Autors:
ALCAMI, J; DELERA, TL; FOLGUEIRA, L; PEDRAZA, MA; JACQUE, JM;

(...)

HAY, RT; HARRICH, D; GAYNOR, RB; VIRELIZIER, JL; ARENZANASEISDEDOS, F.

Referència: EMBO JOURNAL 1995.

Projectes destacats

Generation of HIV immunogens based on the envelope of Founder viruses from patients with broad neutralizing responses

Investigador/a principal: José Alcamí Pertejo, Nuria Gonzalez

Finançador: Instituto de Salud Carlos III (ISCIII)

Codi: MPY 388/23

Durada: 01/01/2024 - 01/01/2026
Ensayo clínico de fase 1 para evaluar la seguridad e inmunogenicidad de la vacuna 763SIP8/MPLA-5 basada en la envoltura del VIH-1 (HIVAC-FOUND)

Investigador/a principal: Josep Mallolas Masferrer

Finançador: Instituto de Salud Carlos III (ISCIII)

Codi: ICI23/00025

Durada: 01/01/2024 - 31/12/2026
Characterization of a mutation in the Transportin 3 gene that protects from HIV infection

Investigador/a principal: José Alcamí Pertejo, Javier García Pérez

Finançador: Ministerio de Ciencia, Innovación y Universidades

Codi: PID2021-125978OB-C21

Durada: 01/01/2023 - 01/01/2025
EAVI 2020: EUROPEAN AIDS VACCINE INITIATIVE 2020

Investigador/a principal: R Shattock, José Alcamí Pertejo

Finançador: Unión Europea

Codi: UE H2020: 681137

Durada: 01/01/2016 - 01/01/2023
Spanish AIDS Research Network

Investigador/a principal: José Alcamí Pertejo

Finançador: Ministerio de Ciencia, Innovación y Universidades

Codi: RD16CIII/0002/01

Durada: 01/01/2016 - 01/01/2022

José Alcamí

Grup de recerca

Publicacions destacades

Projectes destacats

Generation of HIV immunogens based on the envelope of Founder viruses from patients with broad neutralizing responses

Ensayo clínico de fase 1 para evaluar la seguridad e inmunogenicidad de la vacuna 763SIP8/MPLA-5 basada en la envoltura del VIH-1 (HIVAC-FOUND)

Characterization of a mutation in the Transportin 3 gene that protects from HIV infection

EAVI 2020: EUROPEAN AIDS VACCINE INITIATIVE 2020

Spanish AIDS Research Network

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