
Raquel Sanchez-Valle
Cap del Servei de NeurologiaGrup de recerca
- Malaltia d'Alzheimer i altres trastorns cognitius Group leader (R4)
Sobre mi
Vaig completar la meva formació com a neuròloga a l'Hospital Clínic de Barcelona (2000) i el doctorat en Biopatologia de Medicina a la Universitat de Barcelona (UB) (2003). Posteriorment, vaig obtenir una beca Rio Hortega (ISCIII, Ministeri de Sanitat d'Espanya) en neurologia de la conducta a l'IDIBAPS. Vaig realitzar una beca postdoctoral de curt termini al Memory and Aging Center-Universitat de Califòrnia San Francisco, dirigida pel Dr. Bruce Miller (2006). De tornada a Barcelona, em vaig convertir al Group Leader del grup de Malaltia d'Alzheimer i altres trastorns cognitius a l'IDIBAPS i professora associada a la UB (2018). Actualment, sóc cap del Servei de Neurologia de l'Hospital Clínic de Barcelona.
Publicacions destacades
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Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study
Autors: Pérez-Millan A, Borrego-Écija S, van Swieten JC, Jiskoot L, Moreno F, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Tiraboschi P, Seelaar H, Langheinrich T, Rohrer JD, Sala-Llonch R, Sánchez-Valle R, Genetic FTD Initiative, GENFI.Referència: Journal Of Neurology 2023. -
The APOE4 effect: Structural brain differences in Alzheimer's disease according to the age at symptom onset
Autors: Forno G, Contador J, Pérez-Millan A, Guillen N, Falgàs N, Sarto J, Tort-Merino A, Castellví M, Bosch B, Fernández-Villullas G, Balasa M, Antonell A, Sala-Llonch R, Sanchez-Valle R, Hornberger M, Lladó A .Referència: European Journal Of Neurology 2023. -
Classifying Alzheimer's disease and frontotemporal dementia using machine learning with cross-sectional and longitudinal magnetic resonance imaging data
Autors: Pérez-Millan A, Contador J, Juncà-Parella J, Bosch B, Borrell L, Tort-Merino A, Falgàs N, Borrego-Écija S, Bargalló N, Rami L, Balasa M, Lladó A, Sánchez-Valle R, Sala-Llonch R .Referència: Human Brain Mapping 2023. -
Design and validation of the 1-week memory battery for assessing episodic memory and accelerated long-term forgetting in cognitively unimpaired subjects
Autors: Rami L, León M, Valech N, Coll-Padrós N, Bosch B, Olives J, Salinero A, Pérez-Millan A, Molinuevo JL, Sánchez-Valle R, Tort-Merino A .Referència: Neuropsychology 2023. -
Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort
Autors: Sarto J, Ruiz-García R, Guillén N, Ramos-Campoy Ó, Falgàs N, Esteller D, Contador J, Fernández G, González Y, Tort-Merino A, Juncà-Parella J, Bosch B, Borrego-Écija S, Molina-Porcel L, Castellví M, Vergara M, Antonell A, Augé JM, Naranjo L, Sanchez-Valle R, Lladó A, Balasa M .Referència: Neurology 2023. -
Temporal order of clinical and biomarker changes in familial frontotemporal dementia
Autors: Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators.Referència: Nature Medicine 2022. -
CSF Biomarkers in COVID-19 Associated Encephalopathy and Encephalitis Predict Long-Term Outcome
Autors: Guasp M, Muñoz-Sánchez G, Martínez-Hernández E, Santana D, Carbayo Á, Naranjo L, Bolós U, Framil M, Saiz A, Balasa M, Ruiz-García R, Sánchez-Valle R, Barcelona Neuro-COVID Study Group.Referència: Frontiers In Immunology 2022. -
Sex differences in early-onset Alzheimer's disease
Autors: Contador J, Pérez-Millan A, Guillén N, Sarto J, Tort-Merino A, Balasa M, Falgàs N, Castellví M, Borrego-Écija S, Juncà-Parella J, Bosch B, Fernández-Villullas G, Ramos-Campoy O, Antonell A, Bargalló N, Sanchez-Valle R, Sala-Llonch R, Lladó A .Referència: European Journal Of Neurology 2022. -
Barcelona scale for buccophonatory apraxia: quantitative assessment tool
Autors: Montagut N, Borrego-Écija S, Herrero J, Lladó A, Balasa M, Muñoz E, Valldeoriola F, Sánchez-Valle R .Referència: Neurologia 2022. -
Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias
Autors: Antonell A, Tort-Merino A, Ríos J, Balasa M, Borrego-Écija S, Auge JM, Muñoz-García C, Bosch B, Falgàs N, Rami L, Ramos-Campoy O, Blennow K, Zetterberg H, Molinuevo JL, Lladó A, Sánchez-Valle R .Referència: Alzheimers & Dementia 2020.
Projectes destacats
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Genetic dementias (genetic Alzheimer’s disease, frontotemporal dementia and prion diseases): longitudinal changes and expression and epigenetic differences with sporadic cases.
Investigador/a principal: Raquel Sanchez del Valle DíazFinançador: ISCII-Subdireccion General de Evaluacion y el Fondo Europeo de Desarrollo Regional (FEDER)Codi: PI2000448Durada: 01/01/2021 - 31/12/2023 -
Estudio de biomarcadores y desarrollo de nuevas estrategias terapéuticas en una cohorte multicéntrica de Demencia Frontotemporal.
Investigador/a principal: Albert Lleo, Gerard Piñol, Raquel Sanchez del Valle DíazDurada: 01/07/2017 - 31/12/2019 -
Study of genetic frontotemporal dementia in preclinical and early stages of the disease: cognitive performance, structural and functional neuroimaging and biochemical markers (GENFI2-Barcelona)
Investigador/a principal: Raquel Sanchez del Valle DíazCodi: TV3-20143810Durada: 20/05/2015 - 19/05/2020 -
Phase II/III Randomized, Double-Blind, Placebo-Controlled Multi-Center Study of 2 Potential Disease Modifying Therapies in Individuals at Risk for and With Dominantly Inherited Alzheimer's Disease
Investigador/a principal: Raquel Sanchez del Valle DíazDurada: 14/07/2014 -
Alzheimer’s Disease Prediction Service (ADPS): digital biomarker for Real-World Evidence (RWE) in AD
Investigador/a principal: Raquel Sanchez-ValleCodi: EIT Health 18066/2017Durada: 01/01/2018 - 31/12/2018