Sofía Pérez-Del-Pulgar
Publicacions destacades
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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Autors: Álvarez EG, Demeulemeester J, Otero P, Jolly C, García-Souto D, Pequeño-Valtierra A, Zamora J, Tojo M, Temes J, Baez-Ortega A, Rodriguez-Martin B, Oitaben A, Bruzos AL, Martínez-Fernández M, Haase K, Zumalave S, Abal R, Rodríguez-Castro J, Rodriguez-Casanova A, Diaz-Lagares A, Li Y, Raine KM, Butler AP, Otero I, Ono A, Aikata H, Chayama K, Ueno M, Hayami S, Yamaue H, Maejima K, Blanco MG, Forns X, Rivas C, Ruiz-Bañobre J, Pérez-Del-Pulgar S, Torres-Ruiz R, Rodriguez-Perales S, Garaigorta U, Campbell PJ, Nakagawa H, Van Loo P, Tubio JMC .Referència: Nature Communications 2021. -
Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance
Autors: Shekhtman L, Navasa M, Sansone N, Crespo G, Subramanya G, Chung TL, Cardozo-Ojeda EF, Pérez-Del-Pulgar S, Perelson AS, Cotler SJ, Forns X, Uprichard SL, Dahari H .Referència: Elife 2021. -
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients
Autors: García-López M, Lens S, Pallett LJ, Testoni B, Rodríguez-Tajes S, Mariño Z, Bartres C, García-Pras E, Leonel T, Perpiñán E, Lozano JJ, Rodríguez-Frías F, Koutsoudakis G, Zoulim F, Maini MK, Forns X, Pérez-Del-Pulgar S .Referència: Journal Of Hepatology 2021. -
Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation
Autors: Gambato M, Gregori J, Quer J, Koutsoudakis G, González P, Caro-Pérez N, García-Cehic D, García-González N, González-Candelas F, Esteban JI, Crespo G, Navasa M, Forns X, Pérez-Del-Pulgar S .Referència: Journal Of General Virology 2019. -
Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals.
Autors: Perpiñán E, Caro-Pérez N, García-González N, Gregori J, González P, Bartres C, Soria ME, Perales C, Lens S, Mariño Z, Londoño MC, Ariza X, Koutsoudakis G, Quer J, González-Candelas F, Forns X, Pérez-Del-Pulgar S .Referència: Journal Of Viral Hepatitis 2018. -
Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing
Autors: Caro-Pérez N; Martínez-Rebollar M; Gregori J; Quer J; González P; Gambato M; García-González N; González-Candelas F; Costa J; Esteban J; Mallolas J; Forns X; Laguno M; Pérez-del-Pulgar S.Referència: Journal Of Clinical Virology 2017. -
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
Autors: Harak, Christian; Meyrath, Max; Romero-Brey, Ines; Schenk, Christian; Gondeau, Claire; Schult, Philipp; Esser-Nobis, Katharina; Saeed, Mohsan; Neddermann, Petra; Schnitzler, Paul; Gotthardt, Daniel; Perez-del-Pulgar, Sofia; Neumann-Haefelin, Christoph; Thimme, Robert; Meuleman, Philip; Vondran, Florian W. R.; De Francesco, Raffaele; Rice, Charles M.; Bartenschlager, Ralf; Lohmann, Volker;.Referència: Nature Microbiology 2017. -
Hepatitis C Virus RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen
Autors: Gambato M, Pérez-Del-Pulgar S, Hedskog C, Svarovskia ES, Brainard D, Denning J, Curry MP, Charlton M, Caro-Pérez N, Londoño MC, Koutsoudakis G, Forns X .Referència: Gastroenterology 2016. -
Clinical relevance of the study of hepatitis B virus covalently closed circular DNA
Autors: Kumar R., Pérez-del-Pulgar S., Testoni B., Lebossé F., Zoulim F..Referència: Liver International 2016. -
Hepatitis C virus infection inhibits P-body granule formation in human livers
Autors: Pérez-Vilaró G., Fernández-Carrillo C., Mensa L., Miquel R., Sanjuan X., Forns X., Pérez-Del-Pulgar S., Díez J..Referència: Journal Of Hepatology 2015.
Projectes destacats
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Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment
Investigador/a principal: Sofia Perez del Pulgar GallartFinançador: Instituto de Salud Carlos III (ISCIII)Codi: PI16/00111Durada: 01/01/2017 - 31/12/2019 -
Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation
Investigador/a principal: Xavier Forns BernhardtFinançador: Gilead EspañaDurada: 07/03/2016 - 06/03/2018 -
TherVacB: A therapeutic vaccine to cure hepatitis B
Investigador/a principal: Xavier Forns BernhardtCodi: 848223Durada: 01/01/2020 - 31/12/2024 -
Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)
Investigador/a principal: Sofia Perez del Pulgar GallartCodi: PI19/00036Durada: 01/01/2020 - 31/12/2022 -
Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation
Investigador/a principal: Sofia Perez del Pulgar GallartCodi: PI13/00155Durada: 01/01/2014 - 30/03/2017