Sofía Pérez-Del-Pulgar

sofiapp@clinic.cat 0000-0002-9890-300X

Publicacions destacades

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

Autors: Álvarez EG, Demeulemeester J, Otero P, Jolly C, García-Souto D, Pequeño-Valtierra A, Zamora J, Tojo M, Temes J, Baez-Ortega A, Rodriguez-Martin B, Oitaben A, Bruzos AL, Martínez-Fernández M, Haase K, Zumalave S, Abal R, Rodríguez-Castro J, Rodriguez-Casanova A, Diaz-Lagares A, Li Y, Raine KM, Butler AP, Otero I, Ono A, Aikata H, Chayama K, Ueno M, Hayami S, Yamaue H, Maejima K, Blanco MG, Forns X, Rivas C, Ruiz-Bañobre J, Pérez-Del-Pulgar S, Torres-Ruiz R, Rodriguez-Perales S, Garaigorta U, Campbell PJ, Nakagawa H, Van Loo P, Tubio JMC .

Referència: Nature Communications 2021.
Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance

Autors: Shekhtman L, Navasa M, Sansone N, Crespo G, Subramanya G, Chung TL, Cardozo-Ojeda EF, Pérez-Del-Pulgar S, Perelson AS, Cotler SJ, Forns X, Uprichard SL, Dahari H .

Referència: Elife 2021.
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients

Autors: García-López M, Lens S, Pallett LJ, Testoni B, Rodríguez-Tajes S, Mariño Z, Bartres C, García-Pras E, Leonel T, Perpiñán E, Lozano JJ, Rodríguez-Frías F, Koutsoudakis G, Zoulim F, Maini MK, Forns X, Pérez-Del-Pulgar S .

Referència: Journal Of Hepatology 2021.
Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation

Autors: Gambato M, Gregori J, Quer J, Koutsoudakis G, González P, Caro-Pérez N, García-Cehic D, García-González N, González-Candelas F, Esteban JI, Crespo G, Navasa M, Forns X, Pérez-Del-Pulgar S .

Referència: Journal Of General Virology 2019.
Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals.

Autors: Perpiñán E, Caro-Pérez N, García-González N, Gregori J, González P, Bartres C, Soria ME, Perales C, Lens S, Mariño Z, Londoño MC, Ariza X, Koutsoudakis G, Quer J, González-Candelas F, Forns X, Pérez-Del-Pulgar S .

Referència: Journal Of Viral Hepatitis 2018.
Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing

Autors: Caro-Pérez N; Martínez-Rebollar M; Gregori J; Quer J; González P; Gambato M; García-González N; González-Candelas F; Costa J; Esteban J; Mallolas J; Forns X; Laguno M; Pérez-del-Pulgar S.

Referència: Journal Of Clinical Virology 2017.
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Autors: Harak, Christian; Meyrath, Max; Romero-Brey, Ines; Schenk, Christian; Gondeau, Claire; Schult, Philipp; Esser-Nobis, Katharina; Saeed, Mohsan; Neddermann, Petra; Schnitzler, Paul; Gotthardt, Daniel; Perez-del-Pulgar, Sofia; Neumann-Haefelin, Christoph; Thimme, Robert; Meuleman, Philip; Vondran, Florian W. R.; De Francesco, Raffaele; Rice, Charles M.; Bartenschlager, Ralf; Lohmann, Volker;.

Referència: Nature Microbiology 2017.
Hepatitis C Virus RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen

Autors: Gambato M, Pérez-Del-Pulgar S, Hedskog C, Svarovskia ES, Brainard D, Denning J, Curry MP, Charlton M, Caro-Pérez N, Londoño MC, Koutsoudakis G, Forns X .

Referència: Gastroenterology 2016.
Clinical relevance of the study of hepatitis B virus covalently closed circular DNA

Autors: Kumar R., Pérez-del-Pulgar S., Testoni B., Lebossé F., Zoulim F..

Referència: Liver International 2016.
Hepatitis C virus infection inhibits P-body granule formation in human livers

Autors: Pérez-Vilaró G., Fernández-Carrillo C., Mensa L., Miquel R., Sanjuan X., Forns X., Pérez-Del-Pulgar S., Díez J..

Referència: Journal Of Hepatology 2015.

Projectes destacats

Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment

Investigador/a principal: Sofia Perez del Pulgar Gallart

Finançador: Instituto de Salud Carlos III (ISCIII)

Codi: PI16/00111

Durada: 01/01/2017 - 31/12/2019
Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation

Investigador/a principal: Xavier Forns Bernhardt

Finançador: Gilead España

Durada: 07/03/2016 - 06/03/2018
TherVacB: A therapeutic vaccine to cure hepatitis B

Investigador/a principal: Xavier Forns Bernhardt

Codi: 848223

Durada: 01/01/2020 - 31/12/2024

Web: https://www.thervacb.eu/
Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)

Investigador/a principal: Sofia Perez del Pulgar Gallart

Codi: PI19/00036

Durada: 01/01/2020 - 31/12/2022
Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation

Investigador/a principal: Sofia Perez del Pulgar Gallart

Codi: PI13/00155

Durada: 01/01/2014 - 30/03/2017

Sofía Pérez-Del-Pulgar

Publicacions destacades

Projectes destacats

Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment

Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation

TherVacB: A therapeutic vaccine to cure hepatitis B

Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)

Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation

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