Treatment of Age-related Macular Degeneration

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AMD is a degenerative, progressive disease. Age is the main determining factor in all forms of the disease and, therefore, more often than not AMD advances over time, causing a gradual deterioration of your central vision. 

Pill with prescription meds

AMD, prompt diagnosis is important; preferably, in the early stages of the disease. In early and intermediate AMD, oral antioxidant therapy (vitamin and antioxidant supplements) can be prescribed, which has proven effective in slowing disease progression. For advanced dry AMD, the first medications have appeared, but they are not yet approved in Europe. 

Vial

For advanced wet AMD, however, there are several drugs administered through periodic intraocular injections (intravitreal therapy) that slow the progression of the disease. This treatment has dramatically changed the visual prognosis of the disease, as it stabilises vision loss in many cases and, in some cases, improves it. As mentioned, diagnosis of the disease at onset is very important; the earlier the lesion is discovered, the more effective the treatment and the shorter the progression time. 

Cigarette crossed out on a "no smoking" poster

Smoking worsens all forms of AMD. It is the main modifiable risk factor in relation to the condition’s progress.

Doctor performing an E-vision test

There are various specialised optical aids on the market (e.g., filters, magnifiers and electronic systems) which can improve vision quality and be helpful in advanced cases where there is visual impairment. You should consult your preferred optician. 

Substantiated information by:

Javier Zarranz Ventura
Mª Socorro Alforja  Castiella
Ricardo P Casaroli Marano

Published: 20 February 2018
Updated: 11 July 2025

The donations that can be done through this webpage are exclusively for the benefit of Hospital Clínic of Barcelona through Fundació Clínic per a la Recerca Biomèdica and not for BBVA Foundation, entity that collaborates with the project of PortalClínic.

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