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Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...
Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...
Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...
Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...
Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...
Directed by Sabela Lens We investigate the mechanisms of the immune response in chronic HBV and HDV infection to identify determinants of viral co...
Directed by Maria Carlota Londoño Research focuses on autoimmune and cholestatic liver diseases, including autoimmune hepatitis, primary biliary c...
Directed by Xavier Forns We analyze the epidemiology and clinical impact of drug-induced liver injury (DILI), including medications, herbals, and...
After the success of CAR-T cells in hematologic malignancies, the translation of CAR-T cells to solid tumours is the next big challenge in the fiel...
Resistance to CD19-CAR-T cells in hematologic malignancies can appear linked to loss or downregulation of CD19 expression or an immunosuppressive t...
The progress of CAR-T cells is limited by a poor understanding of how the design and signaling of these CAR proteins affect T cell efficacy and per...
While T-cell based immunotherapies have revolutionized cancer treatment, a majority of patients fail to respond or relapse after a certain period o...
New digital technologies have opened a wide range of opportunities and challenges in the mental health field. During the last decade, our team have...
To evaluate clinical and molecular features that may condition disease onset, severity, evolution and co-morbidities. Description of the natural hi...
The strategic objective of this research line is to investigate the genetic, anatomopathological and biochemical bases, as well as the physiopathol...
To search for the physiopatological bases of these diseases we use a combination of the classical and advanced omics technologies (metabolomics, pr...
To confirm the pathogenicity of a certain gene or molecular mechanism, we validate cell models derived from patient to study the disease. We use fi...
This line involves the testing of chemical and peptide libraries, as well as genetic edition strategies. Selection has been made on disease-causing...
Ras proteins are GTPases that regulate signal transduction pathways, which control cell proliferation, differentiation, survival and apoptosis. K-R...
The endolysosomal (LE/Lys) compartment is the main intracellular reservoir of cholesterol and acts as a sorting center from which cholesterol is de...