Resultats de la cerca

• Characterisation of neural substrates of vulnerability to psychosis, and relationship with clinical manifestations, in youth in the early stages of psychosis

  We follow-up youth at different stages of risk for psychosis, defined according to genetic and/or clinical criteria, in comparison with healthy vol...

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• Multimodal prediction of psychosis in high risk youth

  We aim to discriminate between groups and predict clinical and functional outcomes based on a combination of clinical, neurocognitive, neuroimaging...

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• Understanding trajectories of change in brain structure / function leading to health and disease during youth

  We are also interested in understanding brain changes associated with cognitive and physical maturation during healthy development, which we have e...

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• New treatment options for youth with emerging psychosis

  We participate in single and multi-center treatment trials testing non-pharmacological (cognitive behavioural therapy for psychosis) and pharmacolo...

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• Syndromes and mechanisms of paraneoplastic and autoimmune encephalitides

  Directed by Josep Dalmau Our research focuses on the discovery and characterization of autoimmune neurological diseases, particularly those mediat...

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• Prognostic factors in early arthritis

  Prognostic factors (clinical and immunogenetic) in patients with recent-onset rheumatoid arthritis. Production of new synthetic citrullinated an...

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• Clinical and sonographic characterization of clinical remission

  Definition and clinical characterization of subclinical 'active synovitis' Immunopathological and molecular characterization of subclinical 'act...

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• Immunopathology of synovitis in chronic arthritis

  Utility in pathogenesis, differential diagnosis and prognosis of rheumatoid arthritis and psoriatic arthritis. Immunopathological changes induced...

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• Pharmacogenomics of chronic arthritis

  Genetic biomarkers associated with biological therapy response in rheumatoid arthritis and psoriatic arthritis

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• The gut-joint axis in rheumatoid arthritis patients: role of microbiota-induced intestinal T follicular helper cells and innate immune cells in the pathogenesis of the disease

  Collaboration with F. Ciccia (Naples University) and G. Schett (Erlangën University) to know the interaction and physiopathological relevance of...

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• Fetal cardiac programming

  Directed by Fàtima Crispi Understanding the effect of pregnancy complications on fetal cardiac development will allow us to discover preventive st...

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• Fetal brain development

  Directed by Elisenda Eixarch We evaluate the prenatal brain development in the most detailed way possible to be able to select the best markers an...

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• Prematurity

  Directed by Montserrat Palacio Our purpose is to detect the patients with a real risk of premature birth to optimize their treatment and be able t...

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• Inflammation in preterm birth

  Directed by Teresa Cobo We want to predict intra-amniotic infection or inflammation in women at risk of preterm labor using rapid and non-invasive...

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• Fetal therapy & surgery

  Directed by Eduard Gratacós We want to develop new intrauterine therapies and interventions that overcome the current limitations of fetal surge....

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• Placental disease

  Directed by Francesc Figueras We improve the diagnosis and management of pregnancies with growth restrictions and therefore reduce possible altera...

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• Environment and pregnancy complications

  Directed by Oscar García-Algar How do environmental factors such as exposure to tobacco, alcohol, drugs and environmental toxins (heavy metals and...

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• Neurobiological basis of fast-acting antidepressant strategies

  We aim to identify brain circuits involved in fast-acting antidepressant strategies, such as deep brain stimulation or ketamine, which act primaril...

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• Use of RNA interference (RNAi) as a translational strategy in the study of major depressive disorder

  We are using RNAi strategies in vivo in order to modulate the expression of genes involved in the pathophysiology and treatment of major depressive...

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• Role of synucleins in the modulation of monoaminergic neurotransmission: involvement in psychiatric and cognitive aspects of Parkinson’s disease

  Using models of AAV vector-induced overexpression or of RNAi-induced knockdown of α- and γ-synucleins, we are studying their physiological role in...

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