Resultats de la cerca

• 4. Glucocorticoid resistance

  Mechanisms and biomarkers involved in glucocorticoid resistance of respiratory and non-respiratory diseases.

  Investigació – Línies d'investigació

• 5. Aspirin and Non-Steroidal Anti-inflammatory Drug (NSAID) intolerance

  Mechanisms of allergy and co-factors, regulation of cyclooxygenase, leukotriene, and prostaglandins (PGE2) and their receptors.

  Investigació – Línies d'investigació

• 6. Pathophysiology of eosinophils, mast cells, and basophils

  Anaphylactic reactions (mastocytosis, adapter molecules in the signaling of IgE). Antiinflammatory drug effect in eosinophils and epithelial cells...

  Investigació – Línies d'investigació

• 7. Skull base tumours

  Impact of skull base tumours in quality of life and olfaction. Different surgical approaches.

  Investigació – Línies d'investigació

• 1. Cortical network dynamics

  Neuronal and connectivity properties determining the emergent activity generated by neuronal networks. Aspects of spontaneous rhythmic neural activ...

  Investigació – Línies d'investigació

• 2. Brain states

  How is the activity that underlies different brain states, how are the transitions across them and whether we can exogenously induce them.

  Investigació – Línies d'investigació

• 3. Neurotechnology

  We explore new forms to interface the brain, to maintain a dialogue with it by means of recording and stimulation. Currently we are exploring the u...

  Investigació – Línies d'investigació

• 4. Virtual embodiment

  Our brain needs a body that is its interface with the world. Our body can be virtual, and still we can induce 'ownership' over it. We explore how t...

  Investigació – Línies d'investigació

• 1. Clinical, electrical and genetic characteristics of Brugada syndrome

  Since the description of the Brugada syndrome by Pedro and Josep Brugada (team leader), or group been working in the different aspects of this dise...

  Investigació – Línies d'investigació

• 2. Clinical, electrical and genetic characteristics of arrhythmogenic cardiomyopathy

  Arrhythmogenic cardiomyopathy is a hereditary disease of the heart muscle that causes life threatening arrhythmias and progressive heart failure. W...

  Investigació – Línies d'investigació

• 3. Sudden cardiac death without an apparent cause: post-mortem genetic study

  Our group is part of a collaborative effort between the Institut de Medicina Legal de Catalunya, Hospital Josep Trueta (Girona) and Hospital Sant J...

  Investigació – Línies d'investigació

• 4. International collaboration for genome-wide association studies in Brugada and long QT syndrome

  This international collaboration of >70 centres has allowed the identification of common genetic variants that have a strong impact of the predispo...

  Investigació – Línies d'investigació

• 1. Translational research devoted to genomic profiling, assessing mutations and copy number alterations (panels, exome, and, in some cases, whole genome) of lymphoproliferative disorders

  Directed by Armando López-Guillermo.  Assessment of mutations and copy number alterations (exome and whole genome in some cases) of main lymphomas...

  Investigació – Línies d'investigació

• 2. Translational research devoted to study the cellular microenvironment in FL, CLL and other lymphomas

  Directed by Laura Magnano. Microenvironment has demonstrated to be critical in the development of lymphomas, as well as the prognosis and the resp...

  Investigació – Línies d'investigació

• 3. Epidemiological and prognostic studies based on clinical variables and biomarkers linked to the biology of lymphomas

  Directed by Eva Giné. We have participated in several international initiatives to develop prognostic scores based in both clinical variables and...

  Investigació – Línies d'investigació

• 4. New therapies in lymphoproliferative disorders, including developing and performing clinical trials with experimental targeted therapies

  Directed by Julio Delgado. Clinical research with new drugs from academic and pharma trials. Of note is the use of an academic CD-19 CAR- T cell d...

  Investigació – Línies d'investigació

• Dual pathways to insulin replacement: artificial pancreas and beta cell biology

  Directed by Rosa Gasa We combine clinically used artificial‑pancreas technologies with basic research aimed at understanding how beta-cell mass is...

  Investigació – Línies d'investigació

• Metabolic diseases, organ damage, and cardiovascular risk

  Directed by Josep Vidal  We combine clinical and laboratory research to understand how diabetes, dyslipidemia, and obesity lead to organ damage, w...

  Investigació – Línies d'investigació

• Colorectal cancer

  Directed by Dr. Joan Maurel To evaluate intrinsic and acquired mechanisms of resistance to chemotherapy and targeted agents in metastatic colore...

  Investigació – Línies d'investigació

• Brain tumors

  Directed by  Dr. Estela Pineda Identification and characterization of new factors involved in NSC maintenance and differentiation, with a specia...

  Investigació – Línies d'investigació