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We aim to understand how human immunosurveillance shapes the earliest progenitors of cancer (Burdziak et al Science 2023). Most knowledge comes fro...
We use multimodal artificial intelligence to understand how the immune system links diverse clinical conditions. By integrating radiology, patholog...
We design and conduct early-phase clinical trials and investigator-initiated studies to evaluate novel targeted agents and immunotherapies. Close c...
We perform comprehensive molecular and transcriptomic profiling of gastric, pancreatic, and biliary tract tumors to identify oncogenic drivers and...
We develop and validate liquid biopsy technologies that detect tumor-derived nucleic acids in plasma, enabling non-invasive monitoring of tumor dyn...
We create patient-derived organoides (PDOs), xenografts (PDXs), and genetically engineered mouse models that replicate the heterogeneity of upper G...
We investigate how interactions among tumor cells, the immune system, and stromal components affect tumor progression and therapy resistance. Under...
Directed by Albert Herms Lipid droplets are very well characterized in liver, muscle or adipose tissue, but little is known about their role in e...
Directed by Albert Herms Epithelial tissues accumulate mutations as we age. We are applying mouse and human epithelioids, advanced primary self-m...
Directed by Miquel A. Fullana We study the neurobiology of aversive and appetitive learning, primarily using fMRI. These processes have strong tra...
Directed by Laura Rosiñol Dachs Clinical and biological characterization of asymptomatic gammopathies and their progression, study of extramedulla...
Directed by Luis Gerardo Rodríguez CAR-T therapy uses autologous T cells genetically modified. Despite efficacy, relapses occur and questions rema...
Directed by Carlos Fernández de Larrea Cardiac involvement is the main prognostic marker in AL amyloidosis. We assess the impact of combined strat...
Through the previous research line of our experimental lab, our outpatients’ clinic, and our clinical trials team, we participate in the most innov...
Directed by Dr. Fabio Ausania This line is centered on the NOVELLA project, integrating haemodynamic modelling (CFD/AI), preoperative imaging and...
Directed by Dr. Susana de la Luna Protein kinases are central to all cellular processes in eukaryotes and often linked to disease when altered. T...
Directed by Mª Queralt Salas Our research studies the incidence, risk factors, and impact of frailty in adult candidates for allogeneic and autolo...
The group investigates the immune mechanisms underlying autoimmune neurological disorders mediated by antibodies against neuronal and glial surface...
This research axis investigates how viral infections precipitate antibody-mediated autoimmune neurological disorders, using herpes simplex virus ty...
This research axis focuses on identifying antibody correlates of protection and pathogenicity in neuroinfectious and neuroinflammatory disorders. P...