Resultats de la cerca

• Structural and biological mass spectrometry

  We are studying the phosphoproteome, acetylome and ubiquitome of the primary T-cell searching for new substrates of modification involved in TCR-me...

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• Prognostic factors in patients with macular edema associated with non-infectious uveitis

  Assessment of the clinical, biological and imaging factors involved in the pathogenesis of uveitic macular edema and its response to treatment.

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• New biologic therapies for the treatment of non-infectious uveitis

  Assessment of the efficacy and safety of new biologic therapies including anti-TNF-alpha, anti-IL-1beta, and anti-IL-6 receptor monoclonal antibodi...

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• Genetic polymorphisms predisposing to uveitis

  Multicentric study that investigates genetic polymorphisms as potential risk factors for developing uveitis and its complications.

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• Tuberculosis-related uveitis

  Development of epidemiological, clinical and experimental studies.

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• Macular pathology in diabetic patients

  Development of clinical and experimental studies to investigate the pathogenesis of diabetic macular edema, as well as its response to different th...

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• Molecular basis of age-related macular degeneration (AMD)

  Study of the contribution of chronic inflammation and in particular, C-reactive protein and complement Factor H to the progression of AMD.

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• Glaucoma

  Molecular genetics of glaucoma, proteomics of glaucoma secondary to uveitis, and applications of the structural analysis by OCT in glaucoma.

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• Radioguided surgery using virtual technologies

  To create models to merge 3D images in the operating room in real time to detect lesions and improve diagnostic accuracy.    

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• Current and future indications for theragnosis

  Radioligand therapy has proven to be useful in prostate cancer. Emerging indications for other prevalent tumors have opened a new path for oncologi...

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• Efficacy and safety of stroke mechanical thrombectomy techniques

  Mechanical thrombectomy is a groundbreaking treatment for acute ischaemic stroke caused by a large vessel occlusion. Since the beginning of the fir...

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• Radiomics in oncology

  Radiomics is a high-throughput approach to transforming imaging data into a large number of quantitative features and has been utilized in oncology...

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• Radiomics in vascular disease

  Thrombus pathological characteristics potentially impact the efficacy and impact of endovascular treatment and the clinical outcomes of patients wi...

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• Autosomal dominant forms of neurodegenerative dementias and rare dementias

  Directed by Raquel Sánchez-Valle   Sánchez‑Valle’s research focuses on characterizing the earliest stages of autosomal dominant dementia, includin...

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• Sporadic Alzheimer’s disease

  Directed by Albert Lladó Lladó’s research explores the epidemiology, biomarkers, therapies, and social factors in sporadic Alzheimer’s disease. Th...

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• Dementia with lewy bodies and concomitant pathologies in Alzheimer’s disease

  Directed by Mircea Balasa Balasa’s research focuses on validating fluid and imaging biomarkers for earlier and more accurate diagnosis of Dementia...

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• The role of microglia and neuroinflammation in neurodegeneration

  Directed by Anna Martinez-Muriana Martinez-Muriana investigates how microglia and neuroinflammation drive neurodegeneration, with a particular foc...

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• Development and validation of cognitive assessment tools across the healthy aging–Alzheimer’s disease continuum

  Directed by Lorena Rami Rami’s research aims to define the neuropsychological features of the main neurodegenerative dementias. Her team develops...

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• Redox stress in aortic aneurysm formation and progression in Marfan syndrome

  Our aim is to find out which moieties and signaling pathways are impaired in redox physiology and stress in aortic vascular cells. We are also assa...

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• New pharmacological approaches to interfere in the Marfan syndrome-associated TGF-β hypersignaling

  We use TGF-β receptor peptide sequences to sequester soluble active TGF-β in excess to prevent the aortic aneurysm.

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