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This line of research focuses on studying the role of autophagy in the presentation of type 1 diabetes-relevant autoantigens by thymic and peripher...
This projects seeks to engineer novel recombinant pMHC structures suitable for human therapeutic application.
Directed by Dr. Cristina Fillat Pancreatic carcinogenesis is well defined as a multistage process accompanied by distinct morphological and histo...
Directed by Dr. Cristina Fillat Oncolytic adenoviruses replicate in the tumors leading to oncolysis and triggering an immune cell infiltration in...
Directed by Dr. Cristina Fillat Glutaric aciduria type I (GA-I) is a metabolic inherited disease due to mutations in the GCDH gene. Individuals w...
Obtaining MRI and analysis of the arrhythmia substrate using specialized software.
We aim at comprehensively characterizing the molecular mechanisms responsible for sinusoidal cells de-regulation during the progression of liver pa...
Using original bioengineered in vitro models, we aim at describing the effects that modifications in sinusoidal biomechanics, occurring during live...
Considering the increase in worldwide population median age and life expectancy, we devote a significant part of our resources at characterizing, i...
Directed by Elías Campo To characterize the molecular alterations involved in the development and progression of lymphoid neoplasms, particularly...
Directed by Pedro Jares Our research focuses on understanding the molecular mechanisms behind the genomic instability and transcriptional dysregul...
Directed by Lluis Hernández We focus on finding non-coding RNAs (mainly microRNAs and long non-coding RNAs) as biomarkers of interest in the clini...
Observational study to explore the biology of progression in multiple sclerosis using genetic approaches coupled with neuroimage-based tissue pheno...
A randomized controlled clinical study: Study to evaluate the efficacy of cognitive rehabilitation in patients with multiple sclerosis that presen...
Multicentric study within MAGNIMS group. This project is designed to provide high quality information on the changes in structural connectivity in...
We combine computational model simulations with data analysis of electrophysiological single-neuron recordings from collaborating laboratories in o...
We are investigating the specific deficits in working memory of patients recovering from anti-NMDAR encephalitis. We study their behavioral paramet...
We investigate sleep patterns in anti-NMDAR encephalitis patients by recording polysomnogram and EEG longitudinally as patients recover from the di...
NMDAR hypofunction has been hypothesized as a possible mechanism of schizophrenia. By comparing behavioral, EEG and fMRI parameters between anti-NM...
Directed by Marc Claret We have several projects aimed at understanding neuron-type specific mitochondrial biology, from many different angles (d...