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The goal of this line emerges from the recent results derived from the integrative analysis of the proteome and transcriptome from human sperm, ooc...
Exosomes contained in the seminal fluid may contribute proteins and RNAs to the sperm. Our first goal is to characterize the protein and RNA conten...
We have identified a non-random distribution of proteins and genes along the sperm chromatin domains which may represent epigenetic marks involved...
Molecular alterations at the transcriptiomic and proteomic level are analyzed in sperm and seminal plasma from couples with idiopathic infertility...
We are studying the genetic aspects of hereditary endocrine disorders (multiple endocrine neoplasia, congenital adrenal hyperplasia and monogenic...
Differentiated familial thyroid carcinoma represents 3-9% of thyroid carcinomas. Today, the genes involved in some rare syndromic forms in which th...
Oncogenesis is essentially a cell dedifferentiation process. Molecules that induce cell differentiation, such as retinoic acid, have been used for...
We focus on comorbidity (PTSD, liver disease, depression, cognitive impairment, etc.), care integration, and the reduction of health and social in...
Directed by Ángel Chamorro Our research focuses on cerebral microcirculation, particularly microvascular reperfusion failure (no-reflow” phenomeno...
Directed by Anna M. Planas We study immune responses after stroke, from local brain reactions to systemic effects in peripheral organs. Our work f...
Directed by Sergi Amaro This line investigates hemorrhagic stroke, including subarachnoid hemorrhage and intracerebral hemorrhage. Research integr...
Directed by Jose Carlos Fernández-Checa Lipids act as structural molecules, energy sources and signalling factors. Our work has focused on lipid i...
Directed by Carmen Garcia-Ruiz The team research efforts aim to understand the homeostasis and trafficking of cholesterol and sphingolipids in the...
Directed by Pilar Navarro Our research focuses on the molecular mechanisms driving tumor progression, with emphasis on pancreatic cancer, tumor-st...
Directed by Anna Moles Our research investigates tissue remodeling during the onset, progression, and resolution of chronic diseases, with a focus...
Directed by Sandra Torres We study the progression of MAFLD to hepatocellular carcinoma and drug-induced liver injury (DILI), with special attenti...
The use of physiomimetic experimental models is transforming respiratory research by providing biomimetic environments that closely replicate lung...
Development of a stem cell training program based on individual effects of different biomechanical environmental paràmetres to produce highly thera...
Heavily trained athletes have been found to be at a higher risk of atrial fibrillation and right ventricular arrhythmias than their sedentary count...
The deleterious consequences of high-intensity physical activity may not be limited to the heart. We are currently interested in testing whether he...