Resultats de la cerca

• Observational studies in affective disorders

  Our group has led sevral observational studies in bipolar disorder and in depressed patients (such as the BRIDGE study) with recent focus on treatm...

  Investigació – Línies d'investigació

• Psychometrics of mental disorders

  In addition, the research team has developed new clinical scales for the screening of affective disorders and the assessment of cognitive impairmen...

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• Pathophysiology, diagnosis and treatment of portal hypertension

  Directed by Juan Carlos García‑Pagán His research research is centered on the pathophysiology, diagnosis and treatment of portal hypertension and...

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• Mechanisms of liver inflammation and fibrosis

  Chronic liver injury is characterized by an important inflammatory response and an increase in extracellular matrix deposition, which may lead to l...

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• Liver cell plasticity

  The liver has remarkable cell plasticity. Lineage tracing studies have shown the potential of biliary-to-hepatocyte as well as hepatocyte-to-biliar...

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• In vitro disease modeling

  In vitro liver models have emerged as excellent tools to better understand liver pathology, to test new therapeutic drugs and for toxicity testing...

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• Pharmacological, technological and surgical strategies in liver transplantation and surgery

  1. Effect of brain death on steatotic and non-steatotic livers undergoing transplantation Preclinical studies will be carried out to investigate t...

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• A new medical device for transporting abdominal organs in clinical practice

  We intend to develop a new organ transport device which uses a revolutionary technology leading to superior preservation of the organs during trans...

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• New preservation solutions in liver transplantation

  The research carried out by our group to improve the composition of preservation solutions has culminated in the granting of a patent, which has be...

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• Innovations for organ preservation during long times

  Organs and other biological specimens have traditionally been fixed in formaldehyde, which negatively affect many of their intrinsic properties and...

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• To study the regulatory mechanisms and efficacy of stem cell therapy in experimental models and in clinical contexts

  We aim to evaluate the efficacy and safety of stent cell therapy in experimental models of acute and chronic ischemia.

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• To perform experimental models of neointimal hyperplasia, endothelialization, vascular inflammation and thrombosis

  We aim to assess the inflammatory response leading to thrombosis and endothelial healing after coronary injury or therapeutic procedures in experim...

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• To evaluate the influence of hormonal factors, gender and aging in ischemic heart disease

  The objective of this research line is to determine potential factors related to aging in ischemic heart disease experimental models .

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• To design experimental and clinical studies to evaluate the performance of novel devices and strategies to treat coronary artery disease, including chronic and acute coronary syndromes, cardiogenic shock and cardiac arrest

  We aim to test potential new therapeutic devices and strategies by designing clinical trials in patients suffering from acute coronary syndromes, c...

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• To evaluate neurohormonal activation, fibrotic process, genetic and environmental factors associated with ventricular remodeling in dilated cardiomyopathy

  We aim to determine neurohormonal, genetic and environmental factors that are related to the development of ventricular remodeling in patients with...

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• To determine the safety, efficacy and efficiency of new transcatheter and minimally invasive devices to treat structural and congenital heart disease and the role of imaging techniques

  The goal of this project is to test the safety and efficacy of new therapeutic devices in order to treat structural and congenital cardiac defects...

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• To evaluate new pharmacological and invasive treatments for pulmonary hypertension

  The goal of this project is to test the safety and efficacy of new therapeutic approaches (pharmacological and devices) to treat pulmonary hyperten...

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• Neuronal connectivity in Huntington’s disease and other basal ganglia disorders

  Directed by Jordi Alberch Implication of neurotrophic factors and their receptors in the pathophysiology of basal ganglia disorders The study o...

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• RNA and genome regulation in repeat expansion disorders

  Directed by Veronica Brito Our research focuses on RNA and genome regulation in repeat expansion disorders, with particular emphasis on Huntington...

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• Stem cells and regenerative medicine

  Directed by Josep M Canals To study the mechanisms underlying the differentiation of stem cells into specific neuronal populations for cell-base...

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