Resultats de la cerca

• Chronic pain

  Chronic widespread pain (CWP) is a health problem worldwide, with a reported prevalence ranging from 4.2% to 13.3%. The multifaceted reality of CWP...

  Investigació – Línies d'investigació

• Mental health, smoking and other addictions

  Cigarette smoking is the leading preventable cause of death in many countries. Moreover, smokers are more likely than nonsmokers to develop heart d...

  Investigació – Línies d'investigació

• Respiratory diseases

  Respiratory diseases are a common health problem. Many times, people are genetically more likely to get respiratory conditions, but work place or e...

  Investigació – Línies d'investigació

• Digestive and liver diseases

  Digestive and liver diseases are associated with substantial morbidity and mortality in many countries. Statistics about the incidence, prevalence,...

  Investigació – Línies d'investigació

• HIV infection – AIDS and other infectious diseases

  The WHO estimates that one-third of patients with HIV infection in Europe are undiagnosed. This leads to transmission of the infection, late diagno...

  Investigació – Línies d'investigació

• 2.0. health

  The widespread of mobile smartphones among the population has resulted in a growing range of mobile applications in health using iOS and Android de...

  Investigació – Línies d'investigació

• Feeding Behavior, Stress, Social Behavior, and Emotions

  Directed by Marc Claret  We have an original line of research exploring the complex interplay between feeding behavior, stress, emotions, and soci...

  Investigació – Línies d'investigació

• Impact of lifestyle on diabetes

  Diabetes is a serious global health problem due to its prevalence (more than 425 million people), the economic burden and the number of deaths it c...

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• Circulating microRNAs as potential biomarkers and therapeutic targets in type 2 diabetes

  We are interested in finding circulating microRNAs as biomarkers for prediabetes and diabetes, for its micro- and macrovascular complications and f...

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• New therapeutic targets for the treatment of type 2 diabetes and obesity

  The molecular mechanisms underlying the onset and progression of type 2 diabetes is crucial to find novel targets and therapeutic strategies to tre...

  Investigació – Línies d'investigació

• Mechanisms and treatment of endothelial dysfunction in type 2 diabetes

  Diabetes has a detrimental impact on endothelial cell function. In this context, we investigate the impact of glucose oscillations on cardiovascula...

  Investigació – Línies d'investigació

• Bacteremia

  We have been prospectively collecting data on all episodes of bacteremia in the hospital since 1990. This makes it possible to analyze the epidemio...

  Investigació – Línies d'investigació

• Immunocompromised patients

  Register of patients with blood cancer undergoing chemotherapy or bone-marrow transplant. The main areas of study are infections by multiresistant...

  Investigació – Línies d'investigació

• Bone and joint infections

  European Register of Infections/AIDS on joint prostheses, aimed at studying diagnostic methods and the efficacy of new antibiotics in this type of...

  Investigació – Línies d'investigació

• Intestinal microbiota

  We are developing a system to make it possible to perform fecal transplants from healthy volunteers to patients with Clostridium difficile and whic...

  Investigació – Línies d'investigació

• Characterization of the functional impact of driver mutations and the analysis of new potential therapeutic approaches

  Genetic studies have led to the identification of novel recurrent somatic mutations with predicted functional impact, offering new potential therap...

  Investigació – Línies d'investigació

• Development of predictive models recapitulating tumor heterogeneity and their impact on disease evolution, therapy resistance and susceptibility to novel targeted therapies

  Due to the high heterogeneity and complexity of B lymphoid malignancies, the analysis of the effect of novel targeted drugs in different mutational...

  Investigació – Línies d'investigació

• Mechanisms of resistance to targeted therapy

  Treatment with novel targeted drugs like the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib or the Bcl-2 antagonist venetoclax improved outcome...

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• Analyze different biomarkers to predict patients’ outcomes and prognosis

  Patients with different complications of cirrhosis will be prospectively studied. Urine and blood samples will be analyzed to assess the accuracy o...

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• Characterization of systemic and hepatic inflammation and gut microbiome in patients with cirrhosis, encompassing all stages of the disease

  Patients will be divided according to disease stage: from compensated to decompensated and ACLF. Systemic and hepatic inflammation will be investig...

  Investigació – Línies d'investigació