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Analysis of topical and oral photoprotection. Study of UV effect in skin and melanocytic nevi using imaging techniques and high-throughput molecula...
The goal of this line emerges from the recent results derived from the integrative analysis of the proteome and transcriptome from human sperm, ooc...
Exosomes contained in the seminal fluid may contribute proteins and RNAs to the sperm. Our first goal is to characterize the protein and RNA conten...
We have identified a non-random distribution of proteins and genes along the sperm chromatin domains which may represent epigenetic marks involved...
Molecular alterations at the transcriptiomic and proteomic level are analyzed in sperm and seminal plasma from couples with idiopathic infertility...
We are studying the genetic aspects of hereditary endocrine disorders (multiple endocrine neoplasia, congenital adrenal hyperplasia and monogenic...
Differentiated familial thyroid carcinoma represents 3-9% of thyroid carcinomas. Today, the genes involved in some rare syndromic forms in which th...
Oncogenesis is essentially a cell dedifferentiation process. Molecules that induce cell differentiation, such as retinoic acid, have been used for...
Examples: 1) Identification of the pattern of cannabis, tobacco, and alcohol use as a function of gender and psychiatric comorbidities that predic...
Studies at our lab have identified the value of uric acid administration after a brain embolism and how it acts in synergy with reperfusion therapi...
Mechanical thrombectomy (MT) increases brain reperfusion and the likelihood of good outcome in patients with acute stroke but only about one third...
Blood-brain barrier (BBB) disruption is one of the major deleterious mechanisms implicated in the physiopathology of Central Nervous System disease...
Infection is a frequent complication of stroke associated with mortality and poor neurological recovery. Recent experimental studies show that post...
Vascular dementia (VaD) is recognized as one of the leading causes of cognitive impairment and dementia in the elderly, and has become one of the m...
Brain cell death after acute stroke triggers inflammation, involving glial and endothelial cell activation, invasion of leukocytes to the damaged t...
Directed by Jose Carlos Fernández-Checa Lipids act as structural molecules, energy sources and signalling factors. Our work has focused on lipid i...
Directed by Carmen Garcia-Ruiz The team research efforts aim to understand the homeostasis and trafficking of cholesterol and sphingolipids in the...
Directed by Pilar Navarro Our research focuses on the molecular mechanisms driving tumor progression, with emphasis on pancreatic cancer, tumor-st...
Directed by Anna Moles Our research investigates tissue remodeling during the onset, progression, and resolution of chronic diseases, with a focus...
Directed by Sandra Torres We study the progression of MAFLD to hepatocellular carcinoma and drug-induced liver injury (DILI), with special attenti...