Pathophysiology of the NMDAR receptor and personalised medicine for GRIN-related disorders.
Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.
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Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.
Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such...
Study of the ionic channels that regulate the electrical activity of sensory neurons and how they are altered during the pathology. Identification...
To understand how neuron-glia communication contributes to synapse and neuronal loss, and modulates neuronal activity in neurodegeneration. A majo...
Investigation how the activity of synaptic proteins and the synaptic function is affected by physiological and pathological N-glycosylation and its...
This involves obtaining images of the heart’s electrical activity in a noninvasive manner in order to apply this knowledge to developing ablation s...
Study of new physiologic stimulation techniques. Assessment of results and complications.
Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...
Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...
Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...
Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...
Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...
Directed by Sabela Lens We investigate the mechanisms of the immune response in chronic HBV and HDV infection to identify determinants of viral co...
Directed by Maria Carlota Londoño Research focuses on autoimmune and cholestatic liver diseases, including autoimmune hepatitis, primary biliary c...
Directed by Xavier Forns We analyze the epidemiology and clinical impact of drug-induced liver injury (DILI), including medications, herbals, and...
After the success of CAR-T cells in hematologic malignancies, the translation of CAR-T cells to solid tumours is the next big challenge in the fiel...
Resistance to CD19-CAR-T cells in hematologic malignancies can appear linked to loss or downregulation of CD19 expression or an immunosuppressive t...
The progress of CAR-T cells is limited by a poor understanding of how the design and signaling of these CAR proteins affect T cell efficacy and per...
While T-cell based immunotherapies have revolutionized cancer treatment, a majority of patients fail to respond or relapse after a certain period o...
New digital technologies have opened a wide range of opportunities and challenges in the mental health field. During the last decade, our team have...