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Epidemiological multicenter studies on the clinical manifestations and long-term evolution of these diseases Study of IgG4 disease associated wi...
Preclinical development of CARs for the treatment of malignant diseases. Specifically, we have developed a CAR against BCMA, which can be used for...
In this project, funded by the European Research Council (ERC-2015-CoG - 683209_PRIORS), we aim to characterize the neural basis of expectation, an...
During perceptual discrimination task sensory information must be transformed into decision evidence and then temporally integrated in order to yie...
Working memory is the cognitive function describing the maintenance and processing of information in the brain during brief periods of time. The br...
We are developing novel CAR-T cell therapies for the treatment of solid tumours, with a primary focus on breast and ovarian cancers. Studies are un...
We use both NK cells and CAR-NK cells to increase the activity of CART cells avoiding CART cell exhaustion and increasing the antileukemic activity...
GVHD and Infectious complications are the main problems occurring after allogeneic stem cell transplantation, being responsible for a mortality rat...
Our group’s scientific trajectory is focused on the study of the mechanisms involved in the development of haemorrhagic pathologies, particularly t...
Some diseases have a high cardiovascular risk, such as chronic kidney failure, diabetes, and obesity, among others, in which we surmise that endoth...
We have identified certain endothelial damage in the context of transplanted haematopoietic progenitor cells in patients. The behaviour of these ma...
Thrombotic microangiopathies (TMAs) have matching symptoms but may be due to quite different causes. Differential diagnosis of thrombotic thrombocy...
Platelet-derived microparticles facilitate interaction with other cell groups and may have a prothrombotic effect in certain pathological situation...
We have built unique prospective cohorts for the clinical and biological characterization of at-risk and prodromal Parkinson’s disease cohorts, e.g...
We seek, set-up and introduce clinically meaningful biomarkers. Hence, we pioneered the alpha-synuclein seed amplification assay in CSF, being the...
We investigate the pathophysiological mechanisms and pathways to unravel novel therapeutic targets of neurodegenerative movement disorders using hu...
Our group is currently investigating the endogenous phenotype that determines the heterogeneity of pulmonary hypertension in chronic airway obstruc...
To characterize the cell proliferative process that underlies the development of pulmonary hypertension in patients with thromboembolic pulmonary d...
The group is currently involved in a randomized control trial evaluating the impact of a prehabilitation program in the setting of cardiac surgery....
We are working on several physiological proof-of-concept studies and have promoted three international, multicentre, randomized controlled trials.