Resultats de la cerca

• New hereditary genes for colorectal cancer

  Directed by Sergi Castellví We discover new genes for germline predisposition to colorectal cancer. We focus on studying familial (several cases i...

  Investigació – Línies d'investigació

• New hereditary genes for gastric cancer

  Directed by Leticia Moreira We find new genes for germline predisposition to gastric cancer by focusing on early-onset cases. As previously with c...

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• State-of-the-art functional studies of candidate genes

  Directed by Sergi Castellví Candidate genes for colorectal cancer and gastric cancer are evaluated for their ability to predispose for these neopl...

  Investigació – Línies d'investigació

• Clinical relevance of new hereditary genes for gastrointestinal cancer

  Directed by Sergi Castellví We perform a genotype-phenotype correlation of the new genetic variants for germline predisposition to gastrointestina...

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• Molecular and cellular bases of inflammation and remodeling

  We work in the study of the mechanisms involved in the development of systemic inflammatory processes, the role of cell communication mediated by e...

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• Structural and biological mass spectrometry

  We are studying the phosphoproteome, acetylome and ubiquitome of the primary T-cell searching for new substrates of modification involved in TCR-me...

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• Prognostic factors in patients with macular edema associated with non-infectious uveitis

  Assessment of the clinical, biological and imaging factors involved in the pathogenesis of uveitic macular edema and its response to treatment.

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• New biologic therapies for the treatment of non-infectious uveitis

  Assessment of the efficacy and safety of new biologic therapies including anti-TNF-alpha, anti-IL-1beta, and anti-IL-6 receptor monoclonal antibodi...

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• Genetic polymorphisms predisposing to uveitis

  Multicentric study that investigates genetic polymorphisms as potential risk factors for developing uveitis and its complications.

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• Tuberculosis-related uveitis

  Development of epidemiological, clinical and experimental studies.

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• Macular pathology in diabetic patients

  Development of clinical and experimental studies to investigate the pathogenesis of diabetic macular edema, as well as its response to different th...

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• Molecular basis of age-related macular degeneration (AMD)

  Study of the contribution of chronic inflammation and in particular, C-reactive protein and complement Factor H to the progression of AMD.

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• Glaucoma

  Molecular genetics of glaucoma, proteomics of glaucoma secondary to uveitis, and applications of the structural analysis by OCT in glaucoma.

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• Radioguided surgery using virtual technologies

  To create models to merge 3D images in the operating room in real time to detect lesions and improve diagnostic accuracy.    

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• Current and future indications for theragnosis

  Radioligand therapy has proven to be useful in prostate cancer. Emerging indications for other prevalent tumors have opened a new path for oncologi...

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• Efficacy and safety of stroke mechanical thrombectomy techniques

  Mechanical thrombectomy is a groundbreaking treatment for acute ischaemic stroke caused by a large vessel occlusion. Since the beginning of the fir...

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• Radiomics in oncology

  Radiomics is a high-throughput approach to transforming imaging data into a large number of quantitative features and has been utilized in oncology...

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• Radiomics in vascular disease

  Thrombus pathological characteristics potentially impact the efficacy and impact of endovascular treatment and the clinical outcomes of patients wi...

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• Study of genetically determined dementias

  Research line linked to the clinical Genetic counseling program for familial dementias (PICOGEN) at the Hospital Clinic. The first studies were car...

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• Diagnostic and prognostic biomarkers of early-onset sporadic Alzheimer's disease

  The early onset of symptoms, as well as the fact that Alzheimer's disease can present with atypical forms make the diagnosis of these patients chal...

  Investigació – Línies d'investigació