Mostrando 4701 - 4720 de 8759 resultados
Directed by Albert Pol Accumulation of lipid droplets is the cellular hallmark of a plethora of prevalent diseases. Understanding the life-cycle...
Directed by Albert Pol We recently described a new antimicrobial function of cytosolic lipid droplets in the cellular defence against intracellul...
Directed by Marta Bosch Lipid droplets are accumulated in multiple inflammatory processes. With especial attention to the pro-inflammatory transc...
Directed by Albert Pol Lipid droplets are a hallmark of multiple cancers, our research focuses in understanding their role in liquid tumours to d...
This project seeks to define the mechanisms underlying the lineage origin and specification of the autoreactive TR1 cells arising in response to pM...
We seek to define the phenotypic, transcriptional and epigenetic make-up of human autoantigen-specific TR1 cells arising in humanized mice in respo...
This project involves the development of novel methodologies to identify candidate pMHC-based nanomedicines for a variety of chronic inflammatory d...
This line of research focuses on studying the role of autophagy in the presentation of type 1 diabetes-relevant autoantigens by thymic and peripher...
This projects seeks to engineer novel recombinant pMHC structures suitable for human therapeutic application.
Directed by Dr. Cristina Fillat Pancreatic carcinogenesis is well defined as a multistage process accompanied by distinct morphological and histo...
Directed by Dr. Cristina Fillat Oncolytic adenoviruses replicate in the tumors leading to oncolysis and triggering an immune cell infiltration in...
Directed by Dr. Cristina Fillat Glutaric aciduria type I (GA-I) is a metabolic inherited disease due to mutations in the GCDH gene. Individuals w...
Obtaining MRI and analysis of the arrhythmia substrate using specialized software.
We aim at comprehensively characterizing the molecular mechanisms responsible for sinusoidal cells de-regulation during the progression of liver pa...
Using original bioengineered in vitro models, we aim at describing the effects that modifications in sinusoidal biomechanics, occurring during live...
Considering the increase in worldwide population median age and life expectancy, we devote a significant part of our resources at characterizing, i...
Directed by Elías Campo To characterize the molecular alterations involved in the development and progression of lymphoid neoplasms, particularly...
Directed by Pedro Jares Our research focuses on understanding the molecular mechanisms behind the genomic instability and transcriptional dysregul...
Directed by Lluis Hernández We focus on finding non-coding RNAs (mainly microRNAs and long non-coding RNAs) as biomarkers of interest in the clini...
Observational study to explore the biology of progression in multiple sclerosis using genetic approaches coupled with neuroimage-based tissue pheno...