Resultados de búsqueda

• Feeding Behavior, Stress, Social Behavior, and Emotions

  Directed by Marc Claret  We have an original line of research exploring the complex interplay between feeding behavior, stress, emotions, and soci...

  Investigación – Líneas de investigación

• Impact of lifestyle on diabetes

  Diabetes is a serious global health problem due to its prevalence (more than 425 million people), the economic burden and the number of deaths it c...

  Investigación – Líneas de investigación

• Circulating microRNAs as potential biomarkers and therapeutic targets in type 2 diabetes

  We are interested in finding circulating microRNAs as biomarkers for prediabetes and diabetes, for its micro- and macrovascular complications and f...

  Investigación – Líneas de investigación

• New therapeutic targets for the treatment of type 2 diabetes and obesity

  The molecular mechanisms underlying the onset and progression of type 2 diabetes is crucial to find novel targets and therapeutic strategies to tre...

  Investigación – Líneas de investigación

• Mechanisms and treatment of endothelial dysfunction in type 2 diabetes

  Diabetes has a detrimental impact on endothelial cell function. In this context, we investigate the impact of glucose oscillations on cardiovascula...

  Investigación – Líneas de investigación

• Bacteremia

  We have been prospectively collecting data on all episodes of bacteremia in the hospital since 1990. This makes it possible to analyze the epidemio...

  Investigación – Líneas de investigación

• Immunocompromised patients

  Register of patients with blood cancer undergoing chemotherapy or bone-marrow transplant. The main areas of study are infections by multiresistant...

  Investigación – Líneas de investigación

• Bone and joint infections

  European Register of Infections/AIDS on joint prostheses, aimed at studying diagnostic methods and the efficacy of new antibiotics in this type of...

  Investigación – Líneas de investigación

• Intestinal microbiota

  We are developing a system to make it possible to perform fecal transplants from healthy volunteers to patients with Clostridium difficile and whic...

  Investigación – Líneas de investigación

• Characterization of the functional impact of driver mutations and the analysis of new potential therapeutic approaches

  Genetic studies have led to the identification of novel recurrent somatic mutations with predicted functional impact, offering new potential therap...

  Investigación – Líneas de investigación

• Development of predictive models recapitulating tumor heterogeneity and their impact on disease evolution, therapy resistance and susceptibility to novel targeted therapies

  Due to the high heterogeneity and complexity of B lymphoid malignancies, the analysis of the effect of novel targeted drugs in different mutational...

  Investigación – Líneas de investigación

• Mechanisms of resistance to targeted therapy

  Treatment with novel targeted drugs like the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib or the Bcl-2 antagonist venetoclax improved outcome...

  Investigación – Líneas de investigación

• Analyze different biomarkers to predict patients’ outcomes and prognosis

  Patients with different complications of cirrhosis will be prospectively studied. Urine and blood samples will be analyzed to assess the accuracy o...

  Investigación – Líneas de investigación

• Characterization of systemic and hepatic inflammation and gut microbiome in patients with cirrhosis, encompassing all stages of the disease

  Patients will be divided according to disease stage: from compensated to decompensated and ACLF. Systemic and hepatic inflammation will be investig...

  Investigación – Líneas de investigación

• Screening for liver fibrosis. A population-based study in European countries. The 'LiverScreen' project

  The aim of this project is to prove the cost-effectiveness of screening for liver fibrosis in general population using transient elastography.

  Investigación – Líneas de investigación

• Studying different strategies to halt disease progression

  A multicenter, double-blind, placebo controlled randomized clinical trial to study the safety and efficacy of the combination of simvastatin plus r...

  Investigación – Líneas de investigación

• Sleep and sleep disorders

  A clinical and electrophysiological assessment of normal sleep in humans and of sleep disorders including the anti-IgLON5 disease, REM sleep behavi...

  Investigación – Líneas de investigación

• Epilepsy

  Characterization of the epileptogenic activity and the surgical and medical therapy of the refractory epilepsy using functional MRI, video-EEG and...

  Investigación – Líneas de investigación

• Neuropathic pain

  Electrophysiological evaluation of the neuropathic pain using nocioceptive evoked potentials and other tools including the startle reaction.

  Investigación – Líneas de investigación

• Motor control

  Assesment of the motor control in healthy subjects and in patients with neurological diseases using acoustic and somatosensorial stimul and prepulse.

  Investigación – Líneas de investigación