Resultats de la cerca

• Environment and pregnancy complications

  Directed by Oscar García-Algar How do environmental factors such as exposure to tobacco, alcohol, drugs and environmental toxins (heavy metals and...

  Investigació – Línies d'investigació

• Neurobiological basis of fast-acting antidepressant strategies

  We aim to identify brain circuits involved in fast-acting antidepressant strategies, such as deep brain stimulation or ketamine, which act primaril...

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• Use of RNA interference (RNAi) as a translational strategy in the study of major depressive disorder

  We are using RNAi strategies in vivo in order to modulate the expression of genes involved in the pathophysiology and treatment of major depressive...

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• Role of synucleins in the modulation of monoaminergic neurotransmission: involvement in psychiatric and cognitive aspects of Parkinson’s disease

  Using models of AAV vector-induced overexpression or of RNAi-induced knockdown of α- and γ-synucleins, we are studying their physiological role in...

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• Mechanism of action of antidepressant and antipsychotic drugs: identification of new therapeutic targets and brain circuits involved

  As a general objective of the group, we aim at identifying the brain circuits involved in the therapeutic action of drugs used to treat major depre...

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• Molecular mechanisms of inflammation in chronic liver disease

  Studies investigating the molecular mechanisms underlying the inflammatory process commonly observed in chronic liver disease.

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• Therapeutic aspects

  The following lines are mainly focussed on clinical and diagnostic features of HIV & co-infection: HCV and HBV coinfection. Efficacy and safety...

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• Clinical and diagnostic aspects

  Pharmacogenomics and pharmacokinetics Opportunistic diseases associated to HIV infection: tuberculosis, human papillomavirus, anal cancer Sol...

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• Healthcare continuity and management of chronic diseases

  When several diseases coexist in the same patient (comorbidities), care management becomes substantially more complex. In general, there is a growi...

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• Use of healthcare services

  In Spain, which has high life expectancy, an aging population, and universal health care free at the point of use, both the number of persons with...

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• The fragility - geriatrics - dependency - home care axis

  The elderly population will increase in forthcoming decades, making frailty an increasing public health problem. There is evidence of the benefit o...

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• Use of medicines

  Irrational use of medicines is a major problem worldwide. WHO estimates that more than half of all medicines are prescribed, dispensed or sold inap...

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• Primary care and autoimmunity

  Systemic autoimmune diseases (SADs) are a significant cause of morbidity and mortality worldwide, although their epidemiological profile varies sig...

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• Atherogenesis, risk factors and cardiovascular diseases

  Hypertension (HT), smoking, and hypercholesterolemia are the three most common cardiovascular risk factors in Spain. Prevalence of HT in adults > 1...

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• Chronic pain

  Chronic widespread pain (CWP) is a health problem worldwide, with a reported prevalence ranging from 4.2% to 13.3%. The multifaceted reality of CWP...

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• Mental health, smoking and other addictions

  Cigarette smoking is the leading preventable cause of death in many countries. Moreover, smokers are more likely than nonsmokers to develop heart d...

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• Respiratory diseases

  Respiratory diseases are a common health problem. Many times, people are genetically more likely to get respiratory conditions, but work place or e...

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• Digestive and liver diseases

  Digestive and liver diseases are associated with substantial morbidity and mortality in many countries. Statistics about the incidence, prevalence,...

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• HIV infection – AIDS and other infectious diseases

  The WHO estimates that one-third of patients with HIV infection in Europe are undiagnosed. This leads to transmission of the infection, late diagno...

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• 2.0. health

  The widespread of mobile smartphones among the population has resulted in a growing range of mobile applications in health using iOS and Android de...

  Investigació – Línies d'investigació