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Gene expression regulators as a source of novel biomarkers and novel therapeutic targets for digestive cancers
Directed by Dr. Meritxell Gironella Dr. Gironella’s research is mainly focused on the study of small non-coding RNAs and their presence in liquid...
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Endoscopic ultrasonography samples for translational research in the diagnosis of cystic and solid lesions of the pancreas
Directed by Àngels Ginès Dr. Ginès’ research focuses on optimizing the obtention of pancreatic samples, either fluid from pancreatic cystic lesion...
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Genetic immunotherapy for the treatment of cancer and other immune-mediated diseases
Directed by Dr. Manel Juan Otero Development of mainly cell therapies based primarily on T-cells (adoptive immunotherapy: TILs, etc.), though in t...
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Cell therapies in refractory inflammatory bowel disease
Our center is a world leader in autologous hematopoietic stem cell transplant for the treatment of Crohn’s disease. Studies in our group have chara...
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Cross-sectional imaging for the assessment of inflammatory bowel disease
The Magnetic Resonance Index of Activity (MaRIA) is used in specialized centers world-wide. We have developed a simplified index that maintains the...
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Therapeutic targets and biomarkers in inflammatory bowel disease
Inflammatory bowel disease (IBD) develops because of an abnormal immune response to components of the intestinal lumen in genetically predisposed i...
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First and second episodes of schizophrenia
Multicenter, naturalistic, prospective, longitudinal research designed to evaluate clinical, neuropsychological, neuroimaging, biochemical, environ...
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Molecular biology and translational research in schizophrenia
This line of research focuses on brain apoptosis mechanism in FEPs of schizophrenia and the role of antiapoptotic and glutamate inhibitors as a new...
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Neuropsychopharmacology and neuromodulation techniques
This line of research focuses on the efficacy and safety of available antipsychotic drugs, identification of pharmacogenetic variables involved in...
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Neuropsychology, assessment and psychological interventions
Cognitive remediation therapy positively affects cognition and daily functioning in patients with schizophrenia. However, studies on the underlying...
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Pharmacogenetics and schizophrenia
This line focuses on the implementation of pharmacogenetics in clinical practice that allows personalise the therapeutic regimen and establish crit...
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Physical health and morbimortality
Along with other national and international cohorts, we try to consolidate the concept of foetal programming as a physiopathological basis that exp...
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Targeted surgical treatment and quality of life improvement in gynecologic cancers
Directed by: Berta Díaz Feijoo This research line focuses on advancing gynecologic cancer treatment through innovative surgical techniques and per...
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Optimization of the surgical, medical management and follow up of diseases of the reproductive apparatus
To analyze the role of the surgical variables allowing improvement of the results and reduction of the morbidity in the surgical treatment of benig...
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Preservation and improvement of fertility
To evaluate cryopreservation of ovarian tissue and to improve the autotransplantation technique in infertile patients. To improve reproductive outc...
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Reproductive failure markers
To find new markers of hemostasis alterations in early and advanced pregnancy in patients with or without antiphospholipid syndrome and in endometr...
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Robotic surgery and uterine transplantation
To improve and evaluate the current indications for robotic surgery in benign and malignant gynecological diseases, and to overcome the difficultie...
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Molecular therapies and serum biomarkers in liver cancer treatment
Directed by Albert Morales The research led by Dr. Morales focuses in identifying biomarkers, particularly in serum, that may predict treatment ef...
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Immune response in liver chronic disease and cancer development
Directed by Montserrat Marí Dr. Mari’s research aims to understand immune mechanisms activated in chronic liver diseases, to design therapies and...
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Pulmonary hypertension associated with left heart disease and right ventricular dysfunction: identification of new pathophysiological mechanisms, phenotyping and innovative therapeutic strategies.
Pulmonary hypertension associated with left heart disease is a highly heterogeneous condition, representing the most common cause of pulmonary hype...
Investigació – Línies d'investigació