Resultats de la cerca

• Molecular characterization of human NASH-HCC

  We have molecularly characterized human NASH-HCC at the genomic and molecular levels (Pinyol Journal of Hepatology 2021). 

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• Identification of drivers of oncogenesis as targets for therapies in HCC

  Several studies led to the identification of Akt/mTOR pathway [Villanueva Gastroenterology, 2008), EGFR pathway (Keng, Nature Biotech 2009), IGF pa...

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• Establishment of a molecular diagnosis and classification of HCC

  Gene-set (three genes) based diagnosis of HCC reported in Llovet, Gastroenterology 2006, and included in EASL-EORTC guidelines. In addition, we pro...

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• Molecular characterization and identification of drivers of oncogenesis in cholangiocarcinoma

  We have contributed to the molecular classification of iCCA (Sia, Gastroenterology 2013) and eCCA (Montal, Journal of Hepatology 2020).  We identi...

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• Establishment of sorafenib, regorafenib and ramucirumab as standard of care in patients with advanced HCC

  The international RCT showing survival benefits for sorafenib vs placebo, presented at plenary session in ASCO (Llovet, New Engl J Med 2008) was a...

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• Cannabis use disorders and risky cannabis use

  Examples: 1) Influence of introducing the construct of "cannabis risk use" with a co-created formative intervention on cannabis health literacy in...

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• Addictions prevention, addictions workforce & training, and public health

  Examples: 1) Workforce in Addictions - Valorisation in Europe (WAVE) 2) https://interglam.eu/ 3) https://www.deep-seas.eu/ 4) https://far-seas....

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• Digital health and Addictions

  Example: IBM-ABJ: Motivational Brief Intervention combined with Game-Based Learning to improve retention in treatment of patients with alcohol-rela...

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• Genomic alterations in aggressive large B-cell lymphoma

  Directed by Silvia Beà To comprehensively characterize the genetic and molecular profiles of aggressive B-cell lymphomas in order to identify accu...

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• Head Neck Tumors

  Directed by Dr. Isabel Vilaseca, Dr. F. Xavier Avilés and Dr. Neus Basté Multiomic characterisation of head and neck cancer and its impact in a...

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• CAF Plasticity and Heterogeneity in desmoplastic tumors

  We are interested in deciphering and dissecting the plasticity and heterogeneity of cancer-associated fibroblasrs (CAF) during cholangiocarcinogene...

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• Cancer Stem Cells in intrahepatic cholangiocarcinoma

  Combining in vitro and in vivo systems with high throughput transcriptomics and bioinformatics, we aim to elucidate the functional role of cancer s...

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• Tracing Intra-Tumoral Heterogenenity

  Tumors are highly heterogeneous entities, and we are interested in investigating the interactions between heterogeneous cancer cells and the tumor...

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• Thoracic oncology and environmental-related cancer

  Directed by Dr. Laura Mezquita Circulating and tissue biomarkers for immunotherapy in lung cancer Molecular characterization of lung cancer and...

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• Characterization and management of hereditary and familial forms of colorectal cancer

  Directed by Francesc Balaguer Dr. Balaguer's research focuses on the clinical and endoscopic characterization of hereditary and familial forms of...

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• Colorectal cancer screening

  Directed by Antoni Castells Dr. Castells’ research focuses on the evaluation of population-based strategies, assessment of risk factors to advance...

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• Endoscopy for prevention and treatment of colorectal cancer

  Directed by Dr. Maria Pellisé Dr. Pellisé’s research focuses on the implementation of key performance measures and new technologies for improving...

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• Innovation and new technologies in gastrointestinal endoscopy

  Directed by Glòria Fernández-Esparrach Dr. Fernández-Esparrach’s research focuses on the development and evaluation of new technologies to improve...

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• Physiopathology of pancreatic cancer

  Directed by Dr. Eva Vaquero Dr. Vaquero’s research focuses on the study of pancreatic stellate cells as therapeutic target in pancreatic cancer. B...

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• Post-translational control of malignant oncogenic transformation in colorectal carcinogenesis, metastasis, and therapeutic resistance

  Directed by Ester Sánchez-Tilló  The research led by Dr. Sánchez-Tilló seeks new biomarkers of colorectal malignant progression and therapeutic vu...

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