Resultats de la cerca

• Skin and kidney involvement in haematological and systemic diseases

  Studies investigating the morphological findings and molecular mechanisms underlying the inflammatory processes affecting skin and kidney commonly...

  Investigació – Línies d'investigació

• Molecular techniques applied to melanocytic neoplasia, especially to melanoma diagnosis

  Study of molecular features of melanocytic proliferations, focused on differential diagnosis between benign nevus and melanoma.

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• Head and neck carcinomas oncogenesis and prognostic factors

  Molecular studies of carcinomas of the upper respiratory tract, including oncogenetic pathways and translational studies related to prognosis and t...

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• Transcriptional expression profiles involved in molecular mechanisms of carcinogenesis

  We focus mainly on prostate, breast, urologic, skin, gastrointestinal and lung tumors.

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• Genetic and epigenetic diagnosis of autoinflammatory disease

  Directed by Dr. Juan Ignacio Arostegui Extending knowledge of genetic diagnostic tools to improve the determination and management of patients wit...

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• Molecular determination of the T-cell specific immune response

  Directed by Dr. Europa Azucena González Study of the T-cell specific immune response, based on molecular and especially genetic definition of the...

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• Cellular immunotherapy for the treatment of cancer and other immune-mediated diseases

  Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...

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• Molecular and epigenetic mechanisms responsible for the persistent deleterious effects in target tissue exposed to steroidal hormones

  Translational approach in humans and animal models.

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• Neural correlates of mood- and anxiety-related disorders

  Directed by Joaquim Raduà We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brai...

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• Development of neuroimaging-based diagnostic and treatment prediction tools

  Directed by Joaquim Raduà We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and o...

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• Evidence-based syntheses in mental health

  Directed by Joaquim Raduà We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in me...

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• Integrative genetic profile and identification diagnostic markers

  In order to achieve the complete global genetic landscape of these rare tumors we are studying the molecular profile of poorly characterized Non-Ho...

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• Study of intratumoral heterogeneity

  Data already obtained in the analysis of pediatric NHL shows the presence of intratumoral heterogeneity that may represent the existence of differe...

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• Identification of genetic biomarkers and drug targets

  Our final goal is to identify target genes/pathways that can be useful biomarkers in the management of pediatric NHL. In detail, we aim to identify...

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• 1. Ischemia-reperfusion injury and expanding criteria for liver graft acceptance

  Maintaining the viability of organs from their recovery to transplantation is a key factor for transplant success and graft survival. Organ damage...

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• 2. Endoscopic management of biliary complications following liver transplantation

  The study of biliary complications after liver transplantation has high clinical relevance, due it relatively high incidence, complexity of managem...

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• 3. Expanding indications for liver transplantation in relation to pre-existing portal vein thrombosis and portal hypertension

  It is widely known that portal vein thrombosis is a serious complication of chronic liver disease, and the prognosis of liver transplantation depen...

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• 4. Expanding indications for transplantation for malignant tumors – hilar cholangiocarcinoma and colorectal cancer liver metastases

  The decrease in the number of patients on liver transplant waiting lists due to the advent of effective treatment for hepatitis C virus has generat...

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• 5. Alloimmune response, complications associated with immunosupression, and operational tolerance

  Treatment with immunosupression is associated with a series of risks for the transplanted patient, making minimization key to optimizing post-trans...

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• 6. Prevention and treatment of cardiovascular risk factors following liver transplantation

  Cardiovascular diseases represent one of the most common causes of long-term morbidity and mortality after liver transplantation. This group focuse...

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